Apparatus for volumetric tissue ablation

• US 5,827,276 A
• Filed: 12/12/1996
• Issued: 10/27/1998
• Est. Priority Date: 03/24/1995
• Status: Expired due to Term

• Current Assignee: Board of Regents of the University of Nebraska
• Original Assignee: Board of Regents of the University of Nebraska
• Inventors: Fox, Randy, LeVeen, Robert F.
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US08/764,058
• Time in Patent Office: 684 Days
• Field of Search: 606/41, 606/49, 606/50, 607/98, 607/99, 607/113, 607/116, 607/128
• US Class Current: 606/41
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1485 having a short rigid shaft for accessing the inner body through natural openings
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/143 multiple needles
• CPC Class Codes: A61B 2018/1432 curved
• CPC Class Codes: A61B 2018/1475 Electrodes retractable in or deployable from a housing
• CPC Class Codes: A61N 5/045 specially adapted for treatment inside the body

Abstract

A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.

Claims

1. A probe system for penetrating a plurality of electrodes into solid tissue, said probe system comprising:

an elongate member having a proximal end and a distal end;

means for introducing the elongate member through solid tissue; and

at least two solid-tissue-penetrating electrode elements having distal ends reciprocatably attached to the elongate member so that said electrode elements may be advanced into tissue after said elongate member has been introduced through solid tissue to a target site within the tissue, wherein the distal ends of at least some of the electrode elements are shaped so that they assume an outwardly everted configuration as they are axially extended beyond the distal end of the elongate member.

2. A probe system as in claim 1, wherein the elongate member is a tube having an axial lumen which reciprocatably receives the tissue-penetrating electrode elements.

3. A probe system as in claim 2, wherein the introducing means comprises an obturator and sheath assembly, wherein the obturator may be removed from the sheath to leave a lumen within the sheath for receiving the elongate member.

4. A probe system as in claim 3, wherein the obturator is a stylet having a sharpened distal end.

5. A probe system as in claim 2, wherein the introducing means comprises a self-penetrating element disposed at the distal end of the elongate member.

6. A probe system as in claim 1, wherein the tissue-penetrating electrode elements comprise wires which extend through an axial lumen of the elongate member and which have shaped distal ends, wherein the shaped distal ends assume a radially constrained configuration when the wires are axially retracted within said lumen and assume a radially divergent configuration when the wires are axially extended beyond the distal end of the elongate member.

7. A probe system as in claim 1, further comprising at least three electrode elements which are configured in a first group and which extend from a first axial position along the elongate member.

8. A probe system as in claim 7, further comprising at least a second group of three electrode elements which extend from one or more additional axial positions along the elongate member.

9. A probe system as in claim 1, wherein the electrode elements are partially insulated over their regions which are advanced into tissue to define a plurality of active electrode surfaces.

10. A probe system for penetrating a plurality of electrodes into solid tissue, said probe system comprising:

an elongate member having a proximal end and a distal end; and

at least three solid-tissue-penetrating wires reciprocatably attached to the elongate member, wherein said wires have shaped distal ends which assume a radially constrained configuration when the wires are axially retracted within said lumen and which assume an outwardly everted configuration when the wires are axially extended in a distal direction from the elongate member.

11. A probe system as in claim 10, wherein the at least three electrode elements are configured in a first group and which extends from a first axial position along the elongate member.

12. A probe system as in claim 11, further comprising at least a second group of three electrode elements which extend from the elongate member.

13. A probe system as in claim 12, wherein the at least second group of three electrode elements extends from a second axial position spaced-apart from the first axial position of the elongate member.

14. A probe system as in claim 10, further comprising means for introducing the elongate member through solid tissue.

15. A probe system as in claim 14, wherein the elongate member is a tube having an axial lumen which reciprocatably receives the tissue-penetrating electrode elements.

16. A probe system as in claim 15, wherein the introducing means comprises an obturator and sheath assembly, wherein the obturator may be removed from the sheath to leave a lumen within the sheath for receiving the elongate member.

17. A probe system as in claim 10, wherein the electrode elements are partially insulated over their regions which are advanced into tissue to define a plurality of active electrode surfaces.