Apparatus and method for measuring an induced perturbation to determine a physical condition of the human arterial system
First Claim
1. A monitor for use in determining a patient'"'"'s physical condition, comprising:
- an exciter adapted to be positioned over a blood vessel of the patient and configured to induce a transmitted exciter waveform into the patient;
a noninvasive sensor spaced apart from said exciter, adapted to be positioned over said blood vessel and configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of said hemoparameter containing a component of a received exciter waveform; and
a processor coupled to said noninvasive sensor and configured to receive said noninvasive sensor signal and to process said noninvasive sensor signal to determine a physical property of the patient in order to provide a condition signal related to said physical condition.
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Accused Products
Abstract
A monitor for determining a patient'"'"'s physical condition includes a calibration device configured to provide a calibration signal representative of a patient'"'"'s physiological parameter. An exciter is positioned over a blood vessel of the patient for inducing a transmitted exciter waveform into the patient. A noninvasive sensor is positioned over the blood vessel, where the noninvasive sensor is configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of the hemoparameter containing a component of a physiological parameter waveform and a component of a received exciter waveform. In this context, a hemoparameter is defined as any physiological parameter related to vessel blood such as pressure, flow, volume, velocity, blood vessel wall motion, blood vessel wall position and other related parameters. A processor is configured to determine a relationship between a property of the received exciter waveform and a property of the physiological parameter. The processor is connected to receive the calibration signal and the noninvasive sensor signal, and the processor is configured to process the calibration signal and the noninvasive sensor signal to determine the physical condition. In an exemplary embodiment, the physical condition is arterial stiffness that represents cardiovascular disease, however, many additional physical conditions can be measured and determined such as arterial elasticity, arterial thickness, arterial wall compliance and other conditions. Also, in an exemplary embodiment, the physiological parameter measured is blood pressure, however, the present invention can also be used to analyze and track other physiological parameters
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Citations
57 Claims
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1. A monitor for use in determining a patient'"'"'s physical condition, comprising:
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an exciter adapted to be positioned over a blood vessel of the patient and configured to induce a transmitted exciter waveform into the patient; a noninvasive sensor spaced apart from said exciter, adapted to be positioned over said blood vessel and configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of said hemoparameter containing a component of a received exciter waveform; and a processor coupled to said noninvasive sensor and configured to receive said noninvasive sensor signal and to process said noninvasive sensor signal to determine a physical property of the patient in order to provide a condition signal related to said physical condition. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A processor for use in determining a patient'"'"'s physical condition with an apparatus having an exciter positioned over a blood vessel of the patient and configured to induce a transmitted exciter waveform into the patient, and a noninvasive sensor spaced apart from said exciter and adapted to be positioned over said blood vessel and configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of said hemoparameter, said processor comprising:
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a first input configured to receive said noninvasive sensor signal; and a determination routine configured to process said noninvasive sensor signal to determine a physical property of the patient in order to provide a condition signal related to said physical condition. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A method for use in determining a patient'"'"'s physical condition, comprising the steps of:
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inducing a transmitted exciter waveform into the patient at a first location; noninvasively sensing a hemoparameter at a location spaced apart from said first location and generating a noninvasive sensor signal representative of said hemoparameter containing a component of a received exciter waveform; processing said noninvasive sensor signal to determine a physical property of the patient in order to provide a condition signal related to said physical condition. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54)
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55. A monitor for use in determining a patient'"'"'s physical condition, comprising:
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a device configured to provide a pressure signal representative of a blood pressure of the patient; an exciter adapted to be positioned over a blood vessel of the patient and configured to induce a transmitted exciter waveform into the patient; a noninvasive sensor spaced apart from said exciter and adapted to be positioned over said blood vessel from said exciter and configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of said hemoparameter containing a component of a received exciter waveform; and a processor coupled to said noninvasive sensor and configured to receive said noninvasive sensor signal and said pressure signal and to process said noninvasive sensor signal and said pressure signal to determine a physical property of the patient in order to provide a condition signal related to said physical condition. - View Dependent Claims (56, 57)
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Specification