Intravascular catheter probe for clinical oxygen, pH and CO.sub.2 measurement
First Claim
1. A detection device for tissue oxygen and/or pH (CO2) measurement in animals and humans comprising fiber optics means for transmitting emitted phosphorescent and/or fluorescent light, a probe at one end of the fiber optic means comprising a portion of the fiber optic means enclosed by a gas-permeable film, and a reservoir of a liquid which contains an oxygen quenchable phosphorescence emitting oxygen sensor and/or a fluorescence emitting pH sensor situated between the gas-permeable film and the fiber optic means, and further comprising at the other end of the fiber optic means phosphorescent and/or fluorescent detecting means and excitation light emitting means.
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Accused Products
Abstract
Methods and apparatus for the measurement of oxygen, pH and CO2 in human and animal tissue is provided, in which the compounds preferably include a chromophore and/or fluorphor capable of absorbing an amount of energy and subsequently releasing the energy as phosphorescent and/or fluorescent light, and wherein the phosphorescence is quenched by molecular oxygen according to the Stern-Volmer relationship, CO2 is measured by fluorphor which alters fluorescence with pH.
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Citations
22 Claims
- 1. A detection device for tissue oxygen and/or pH (CO2) measurement in animals and humans comprising fiber optics means for transmitting emitted phosphorescent and/or fluorescent light, a probe at one end of the fiber optic means comprising a portion of the fiber optic means enclosed by a gas-permeable film, and a reservoir of a liquid which contains an oxygen quenchable phosphorescence emitting oxygen sensor and/or a fluorescence emitting pH sensor situated between the gas-permeable film and the fiber optic means, and further comprising at the other end of the fiber optic means phosphorescent and/or fluorescent detecting means and excitation light emitting means.
Specification