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Methods for making immunoisolatory implantable vehicles with a biocompatiable jacket and a biocompatible matrix core

  • US 5,834,001 A
  • Filed: 05/24/1995
  • Issued: 11/10/1998
  • Est. Priority Date: 04/25/1991
  • Status: Expired due to Term
First Claim
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1. A method of forming an implantable and retrievable immunoisolatory vehicle, the method comprising the steps of:

  • (a) forming a jacket of biocompatible thermoplastic or hydrogel, and(b) loading said jacket with a core comprising a volume of at least 1 μ

    l and at least 104 cells capable of secreting a biologically active product or biocompatible matrix comprising a hydrogel, said jacket having a molecular weight cutoff permitting passage of molecules thereacross to provide said biologically active product of said function.

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