Method and apparatus for metering a fluid

• US 5,834,314 A
• Filed: 08/06/1997
• Issued: 11/10/1998
• Est. Priority Date: 11/07/1994
• Status: Expired due to Term

• Current Assignee: Abbott Laboratories
• Original Assignee: Abbott Laboratories
• Inventors: Gates, James D., Li, Conan K. N., Pan, Jeffrey Y., Huang, Tung-Ming, Egan, Karen A., Alcock, Alan J., Ver Lee, Donald
• Primary Examiner(s): LUDLOW, JAN M
• Application Number:
  US08/907,143
• Time in Patent Office: 461 Days
• Field of Search: 422/81, 422/82, 422/100, 436/52, 436/53
• US Class Current: 436/52
• CPC Class Codes: F16K 7/17 the diaphragm being actuated by fluid pressure
• CPC Class Codes: G01N 35/08 using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
• CPC Class Codes: G01N 35/1097 characterised by the valves valves in general F16K
• CPC Class Codes: Y10T 436/117497 with a continuously flowing sample or carrier stream
• CPC Class Codes: Y10T 436/118339 with formation of a segmented stream

Abstract

Embodiments disclosed involve methods and constructions for metering, and in some instances combining, fluids. One such method includes fluidly connecting a source of first fluid to be metered with a pressure source capable of moving the first fluid with a first valve and a conduit. The first valve is operated such that first fluid moves in the conduit. The conduit is fluidly connected with a source of second fluid that has a fluid flow rate greater than the first fluid with a second valve. The second valve is operated such that the second fluid moves into the conduit. One construction for metering a fluid comprises a source of first fluid to be metered, a pressure source for moving the first fluid to be metered, and a first valve. A conduit fluidly connects the source of first fluid, the pressure source for moving the first fluid and the first valve such that operation of the first valve causes movement of the first fluid responsive to the pressure source. A second valve fluidly connects a source of second fluid that has a fluid flow rate greater than the first fluid with the conduit such that operation of the second valve causes movement of the second fluid into the conduit.

Claims

1. A method for metering a first fluid, the method comprising the steps of:

(a) fluidly connecting a source of first fluid to be metered with a pressure source capable of moving the first fluid, the source of first fluid being fluidly connected with the pressure source by a first valve and a conduit;

(b) operating the first valve such that the first fluid moves in the conduit;

(c) operating the first valve so that the first valve defines a first end of a metered volume in a first portion of the conduit;

(d) fluidly connecting the pressure source with a source of second fluid that has a fluid flow rate greater than the first fluid with a second valve and a second portion of the conduit; and

(e) operating the second valve such that the second fluid moves into the second portion of the conduit simultaneously with movement of the first fluid in the second portion of the conduit to provide said metered volume of the first fluid in the first portion of the conduit with the second valve defining an end of the metered volume of the first fluid in the first portion of the conduit, the metered volume being contained in the first portion of the conduit between the first and second valves.

2. A method as defined in claim 1 further comprising the step of:

(f) repeating steps (a), (b), (c), (d), and (e) to meter multiple volumes of fluid.

3. A method as defined in claim 1 further comprising the step of:

(f) bounding the first fluid within the conduit with the second fluid.

4. A method as defined in claim 1 further comprising the step of:

(f) detecting movement of the first fluid within the conduit.

5. A method as defined in claim 1 further comprising the step of:

(f) insuring that first fluid does not reach the pressure source.

6. A method as defined in claim 1 further comprising the step of:

(f) positively controlling operation of the pressure source to reduce at least one of bubble formation in, outgassing of, turbulence in and mixing of first fluid and second fluid.

7. A method as defined in claim 1 further comprising the step of:

(f) positively controlling a time period between operation of the first valve and operation of the second valve.

8. A method as defined in claim 1 further comprising the step of:

(f) predetermining dimensions of the conduit such that the dimensions of the conduit correspond to a volume of fluid to be metered.

9. A construction for metering a first fluid comprising:

(a) a source of first fluid to be metered;

(b) a constant pressure source for moving the first fluid to be metered;

(c) a first valve;

(d) a controller;

(e) a conduit fluidly connecting the source of first fluid, the constant pressure source for moving the first fluid and the first valve, the first valve connected to the controller, wherein the controller operates the first valve to cause movement of the first fluid responsive to the constant pressure source, and the controller operates the first valve so that the first valve defines a first end of a metered volume in a first portion of the conduit;

(f) a source of second fluid that has a fluid flow rate greater than the first fluid; and

(g) a second valve fluidly connecting the source of second fluid with the constant pressure source and a second portion of the conduit, the second valve connected to the controller, wherein the controller operates the second valve to cause movement of the second fluid into the second portion of the conduit simultaneously with movement of the first fluid in the second portion of the conduit to provide said metered volume of the first fluid in the first portion of the conduit with the second valve defining an end of the metered volume of the first fluid in the first portion of the conduit, the metered volume being contained in the first portion of the conduit between the first and second valves.

10. A construction as defined in claim 9 further comprising:

(h) a detector operatively associated with the conduit for detecting fluid within the conduit.

11. A construction as defined in claim 9 further comprising:

(h) a timer connected to the controller operatively connected with the first valve and the second valve for monitoring a time period between operation of the first valve and operation of the second valve.

12. A construction as defined in claim 9 wherein the first portion of the conduit has dimensions corresponding to a volume of fluid to be metered.