Implantable infusion pump

• US 5,836,915 A
• Filed: 09/18/1995
• Issued: 11/17/1998
• Est. Priority Date: 09/16/1994
• Status: Expired due to Term

• Current Assignee: Aqulinx Medical, Inc.
• Original Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Inventors: Wild, Andreas, Steinbach, Bernd, Walter, Claus
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US08/529,776
• Time in Patent Office: 1,156 Days
• Field of Search: 604/131, 604/132, 604/140, 604/141, 604/143, 604/145, 604/151, 604/153
• US Class Current: 604/131
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

The invention concerns an implantable infusion pump for dosed emission of medicines into the human body comprising a pump chamber formed by an upper chamber portion (3) and a lower chamber portion (2), whereby said pump chamber is divided by a flexible membrane (6) into a pressure chamber (8) and a medicine reservoir (7). Refill apertures (12, 14) covered by septa (13, 15) are further provided. The septa (13, 15) are hermetically clamped by holders (4, 5). According to the invention, catch connections are used as main connections (31, 32, 33) and as ancillary connections (34, 35) for the connection of the pump components (2, 3, 4, 5), whereby the main connections (31, 32, 33) substantially support the interior pressure strain generated under normal operating load and the locked ancillary connections (34, 35) are hereby not or only nimimally brought into operation due to respective arrangement and dimensioning of the catch members. The ancillary connections (34, 35) are only activated in the case of a further pressure increase due to overload or failure of the main connections (31, 32, 33).

Claims

1. Implantable infusion pump for dosed emission of medicines into the human body,

comprising a pump chamber formed by a lower chamber portion and an upper chamber portion connected thereto, whereby

the pump chamber is separated by a flexible membrane into two sectional chambers, of which the first sectional chamber is defined by the upper chamber portion and the membrane and is formed as the medicine reservoir, the upper chamber portion comprises a refill aperture sealed by at least one pierceable septum which is locked between a septum holder part connected to the upper chamber portion and the upper chamber portion,

the medicine reservoir is connected through an outlet aperture and an outlet reducer means with an outlet catheter and

the second sectional chamber is defined by the lower chamber portion and the membrane and is formed as a pressure chamber to accommodate a motive substance, and wherein internal pressure strain is generated under normal operating load;

the infusion pump comprising;

the lower chamber portion and the upper chamber portion being in engagement by at least two associated connections, one of which being a main connection located proximal to said chambers and the other of which being an ancillary connection located distal to said chambers whereby the

the main connection substantially supports the infusion pump against said internal pressure strain generated under normal operating load and, in the case of deformation of the lower chamber portion, the upper chamber portion and the septum holder part or slippage between the upper chamber portion and the lower chamber portion caused by a pressure increase above normal operating pressure and in the case of failure or deflection of the main connection, the ancillary connection is subjected to corresponding stress and supports the infusion pump against the pressure overload.

2. Implantable infusion pump according to claim 1, wherein at least two connections are formed by catch members as catch connections.

3. Implantable infusion pump according to claim 2, wherein the infusion pump is formed as a disc-shaped body with rounded disc edges and made of plastic and the catch connections are formed as main and ancillary connections with concentric annular catch slots engaged by associated latches carried by annular bars.

4. Implantable infusion pump according to claim 3, wherein the refill aperture is centered and the septum is a disc-shaped central septum, a concentric annular slot to whose inner and outer lateral wall circumferential catch slots are respectively attached is molded onto the upper chamber portion, the septum holder part is formed as a ring which overlaps the edges of the central septum and comprises two parallel annular bars which extend into the annular slot and respectively engage with the catch slots of annular slot by latches, whereby the two connections on both catch slots form a main connection and an associated ancillary connection.

5. Implantable infusion pump according to claim 4, wherein the connection on the outer catch slot forms the main connection and the connection on the inner catch slot forms the ancillary connection.

6. Implantable infusion pump according to claim 5, wherein on the upper inner edge area of the disc-shaped lower chamber portion an annular slot is provided, into which a circumferential associated edge of the upper chamber portion is clamped together with an O-ring and the edge of the membrane in a catch connection forming a main connection, on the outer lateral edge area of the lower chamber portion a further annular slot is provided, into which a latch arrangement of an annular overlap part engages in a catch connection formed as an associated ancillary connection, whereby the overlap part overlaps the upper chamber portion and the outer lateral edge area of the lower chamber portion in bell-shape arrangement and finds support on the upper chamber portion.

7. Implantable infusion pump according to claim 6, wherein an annulus is formed between an outer wall area of the upper chamber portion and an inner wall area of the overlap part.

8. Implantable infusion pump according to claim 7, wherein the annulus is formed to accommodate the outlet reducer means and the outlet catheter.

9. Implantable infusion pump according to claim 8, wherein an annulus surrounding the annular slot is formed on the outer wall of the upper chamber portion, and said annulus is covered and sealed by an annular septum, the edge of the annular septum pointing to the annular slot is covered and clamped by an outer edge of the annular septum holder member,

the outer edge of the ring of the annular septum is covered and clamped by an edge area of the overlap part, and

in this edge area of the overlap part a catch connection between the overlap part and the upper chamber portion comprising a catch slot and catch bars having circumferential latches engaging into said catch slot is provided, preferably a catch slot on the overlap part and a circumferential latch on the upper chamber portion, and

this catch connection represents a main connection and the catch connection between the lower chamber portion and the overlap part represents an associated ancillary connection.