Endoprosthesis

• US 5,836,962 A
• Filed: 01/22/1997
• Issued: 11/17/1998
• Est. Priority Date: 10/20/1993
• Status: Expired due to Term

• Current Assignee: Boston Scientific Corporation
• Original Assignee: Schneider (Europe) GmbH (Boston Scientific Corporation)
• Inventors: Gianotti, Marc
• Primary Examiner(s): Dawson, Glenn K.
• Application Number:
  US08/787,817
• Time in Patent Office: 664 Days
• Field of Search: 606/108, 606/151, 606/228, 606/232, 606/191, 606/200, 623/1, 623/11, 623/12, 428/373
• US Class Current: 623/1.51
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body

Abstract

A body compatible device including an elongate filament substantially uniform in lateral cross-section over its length and having multiple fibers having high tensile strength embedded in a polymeric material. The polymeric material may be melted onto the fibers, and the filament may have an elongate polymeric case surrounding the filament. The body compatible device may be a stent of a tubular latticework.

Claims

1. An endoprosthesis for use in vessels of the human or animal body, comprising each of said filaments including a tubular latticework made of flexurally rigid elastic filaments, each of said filaments including a core element of high tensile strength and a shell which surrounds the core element and does not substantially alter the tensile strength of the filament, the shell being designed to receive active substances, wherein the core element consists of a composite material, the composite material being made up of a plurality of high tensile strength, elements which, for the purpose of achieving a high flexural rigidity of the filament, are sheathed by a support material of low tensile strength, and the shell is anchored unreleasably on the support material.

2. The endoprosthesis according to claim 1 wherein both the support material and the shell each comprise a thermoplastic, and the thermoplastic of the support material is melted and fused together with the thermoplastic of the shell material.

3. The endoprosthesis according to claim 2 wherein the shell contains the same thermoplastic as the support material.

4. The endoprosthesis according to claim 1 wherein the support or the shell material is prepared from a mixture of substances which contain a contrast medium.

5. The endoprosthesis according to claim 1 wherein material located on the filament exterior and comprising the shell is prepared from a mixture of substances, which contain a medication effective in a human or animal body.

6. The endoprosthesis according to claim 1 wherein the support material has a surface on which the shell is anchored.

7. The endoprosthesis according to claim 1 wherein material located on the filament exterior and comprising the shell has pores in which a medication effective in the human or animal body is stored.

8. The endoprosthesis of claim 1 wherein the shell is porous and contains a medically active substance in its pores.

9. A body compatible stent comprising at least two interwoven sets of elongate, resilient elements substantially uniform in lateral cross-section over their lengths and forming a tubular latticework which is compressible upon radially internally directed forces to a reduced diameter and self-expandable upon release of the radially internally directed forces to an expanded diameter, wherein the elements comprise:

(a) multiple fibers having high tensile strength;

(b) a first thermoplastic material embedding the fibers to form a composite; and

(c) a second thermoplastic material embedding the composite.

10. The stent of claim 9 wherein the fibers comprise inorganic polymeric fibers.

11. The stent of claim 9 wherein the fibers comprise carbon, Kevlar aramide fibers, glass, or combinations thereof.

12. The stent of claim 9 wherein the first thermoplastic material is polyetheretherketone or polyethersulfone.

13. The stent of claim 9 wherein the first and second thermoplastic materials are, the same polymeric materials.

14. The stent of claim 9 wherein the first polymeric material is melted onto the fibers.

15. The stent of claim 9 wherein the first polymeric material and/or the second polymeric material contain a contrast medium.

16. A body compatible stent comprising at least two interwoven sets of elongate, resilient elements substantially uniform in lateral cross-section over their lengths and forming a tubular latticework which is compressible upon radially internally directed forces to a reduced diameter and self-expandable upon release of the radially internally directed forces to an expanded diameter, wherein the elements comprise:

(a) multiple polymeric fibers having high tensile strength;

(b) a first thermoplastic material embedding the fibers to form a composite; and

(c) a second thermoplastic material embedding the composite and forming a porous exposed outermost surface on the elements which includes a medically active material within its pores.

17. The stent of claim 16 wherein the polymeric fibers comprise inorganic fibers.

18. The stent of claim 16 wherein the polymeric fibers are carbon, Kevlar aramide fibers, glass, or combinations thereof.

19. The stent of claim 16 wherein the first thermoplastic material is polyetheretherketone or polyethersulfone.

20. The stent of claim 16 wherein the first and second thermoplastic materials are the same polymeric materials.

21. The stent of claim 16 wherein the first polymeric material is melted onto the fibers.

22. The stent of claim 16 wherein the first polymeric material and/or the second polymeric material contain a contrast medium.