Radio frequency energy delivery system for multipolar electrode catheters

• US 5,837,001 A
• Filed: 12/08/1995
• Issued: 11/17/1998
• Est. Priority Date: 12/08/1995
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: C. R. Bard
• Inventors: Mackey, Sean
• Primary Examiner(s): JAWORSKI, FRANCIS J
• Application Number:
  US08/569,771
• Time in Patent Office: 1,075 Days
• Field of Search: 606/31-33, 606/38, 606/42, 607/101-102, 607/122
• US Class Current: 607/102
• CPC Class Codes: A61B 18/12 by passing a current through the tissue to be heated, e.g. high-frequency current
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00595 Cauterization
• CPC Class Codes: A61B 2018/0066 without feedback, i.e. open loop control
• CPC Class Codes: A61B 2018/00666 using a threshold value
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00708 switching the power on or off
• CPC Class Codes: A61B 2018/0075 Phase
• CPC Class Codes: A61B 2018/00767 Voltage
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00815 measured by a thermistor
• CPC Class Codes: A61B 2018/00821 : measured by a thermocouple
• CPC Class Codes: A61B 2018/00827 : Current
• CPC Class Codes: A61B 2018/00875 : Resistance or impedance
• CPC Class Codes: A61B 2018/00892 : Voltage
• CPC Class Codes: A61B 2018/1253 : monopolar
• CPC Class Codes: A61B 2018/1273 : including multiple generators in one device

Abstract

A radio-frequency ablation system is disclosed in which the power, voltage, or temperature delivered to multiple electrodes may be dynamically controlled, and in which the electrodes may be simultaneously energized in phase with each other to achieve a desired lesion pattern. The system comprises a multiple electrode ablation catheter, each electrode having a temperature sensor operatively associated therewith. Each electrode is energized by its own RF amplifier, and all of the electrodes are driven in phase with each other by a common sine wave oscillator. A feedback network controls the degree of amplification of the separate RF amplifiers. According to a further aspect of the invention, a modular power supply arrangement is disclosed which is configurable to dynamically control the power, voltage, or temperature delivered to multiple electrodes of a multipolar ablation device. An arbitrary number of electrodes may be simultaneously energized in phase with each other to achieve a desired lesion pattern using the modular power supply by providing a sufficient number of removable modules.

Claims

1. A radio-frequency ablation system for biological tissues, comprising:

an electrode catheter having a generally longitudinally extending shaft defining a lumen and an array of externally conductive, individually connected electrodes arranged in spaced serial relation along said shaft;

a plurality of temperature sensors, each thermally associated with a different electrode in said array for providing a temperature signal representative of the temperature of that electrode;

a plurality of RF amplifiers, each electrically connected to a different electrode in said array, each of said RF amplifiers providing drive signals representative of the voltage and current applied to that electrode;

a feedback control network which receives said temperature and drive signals associated with a particular electrode and provides an amplification signal to the RF amplifier connected to that electrode in response to the received temperature and drive signals; and

a RF sine wave oscillator having an output which is separately amplified in phase by each of said RF amplifiers in accordance with the amplification signal from the feedback control network for that RF amplifier, to independently drive each of the electrodes in the array of electrodes in phase with each other.

2. The radio-frequency ablation system as in claim 1, wherein each of the electrodes in said array of electrodes is driven simultaneously at differing levels of amplification.

3. The radio-frequency ablation system as in claim 1, wherein said feedback control network returns an amplification signal to maintain the temperature of an electrode constant.

4. The radio-frequency ablation system as in claim 1, wherein said feedback control network returns an amplification signal to maintain the power through an electrode constant.

5. The radio-frequency ablation system as in claim 1, wherein said feedback control network returns an amplification signal to maintain the voltage through an electrode constant.

6. The radio-frequency ablation system as in claim 1, wherein said electrodes are spaced such that the power delivered to adjacent electrodes spans the tissue between said adjacent electrodes sufficient to cause a continuous lesion to form.

7. The radio-frequency ablation system as in claim 1, wherein successive adjacent electrodes in said array are spaced at different predetermined distances.

8. The radio-frequency ablation system as in claim 1, further comprising a return electrode connected to a ground potential output of said RF amplifiers.

9. The radio-frequency ablation system as in claim 1, wherein one of said electrodes in said array is disposed at the catheter distal tip, and the remaining electrodes in said array are ring electrodes surrounding said shaft.

10. The radio-frequency ablation system as in claim 1, wherein said temperature sensor is one of a thermocouple, thermistor, or resistive thermal device.