Cardioplegia monitoring system, flow cell cassette, variable ratio valve, and method

• US 5,837,905 A
• Filed: 07/24/1996
• Issued: 11/17/1998
• Est. Priority Date: 07/24/1996
• Status: Expired due to Fees

• Current Assignee: Gish Biomedical, Inc. (LivaNova Plc)
• Original Assignee: Gish Biomedical, Inc. (LivaNova Plc)
• Inventors: Strauss, Brian, Galt, Kenneth M., White, George W.
• Primary Examiner(s): Dombroske, George M.
• Assistant Examiner(s): AMROZOWICZ, PAUL DOUGLAS
• Application Number:
  US08/690,259
• Time in Patent Office: 846 Days
• Field of Search: 73/861.63, 73/727, 73/706, 73/721, 73/726, 128/672, 128/675, 128/691, 128/748, 604/4
• US Class Current: 73/861.63
• CPC Class Codes: A61M 1/36226 Constructional details of cassettes, e.g. specific details on material or shape
• CPC Class Codes: A61M 1/362262 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/3663 Flow rate transducers; Flow integrators
• CPC Class Codes: A61M 1/3664 for preparing cardioplegia solutions
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/366 by liquid heat exchangers
• CPC Class Codes: A61M 2209/082 Mounting brackets, arm supports for equipment
• CPC Class Codes: A61M 39/223 Multiway valves

Abstract

A system and method for delivery of cardioplegic solution to the heart of a patient incorporates novel venturi flow cells individually adapted for insertion in the blood and crystalloid solution lines together with transducers for measuring a pressure drop across each venturi flow cell and transmitting it to a microprocessor to calculate flow rate for display on a monitor. The novel self-venting and self-priming transducers and venturi flow cells are incorporated in a disposable cassette. The transducers in the disposable cassette are removably snap connected to a hand set or plug housing which communicates with the computer or microprocessor and monitor. A novel variable ratio valve permits infinitely variable ratios of blood and crystalloid solution.

Claims

1. An assembly for administering cardioplegia comprising in combination:

at least one venturi flow cell for blood;

at least one venturi flow cell for crystalloid solution;

at least one means for connecting a crystalloid solution for flow through said at least one venturi flow cell for crystalloid solution;

at least one means for connecting a source of blood for flow through said at least one venturi flow cell for blood;

each said at least one venturi flow cell for blood and said at least one venturi flow cell for crystalloid solution comprising;

a tubular member;

a constriction formed within said tubular member to divide said tubular member into a convergent portion and a divergent portion;

a first port in communication with said convergent portion of said tubular member;

a second port in communication with said constriction;

at least one transducer connected to said first port and to said second port for detecting a pressure drop between said first port and said second port respectively when crystalloid solution is caused to flow through said at least one venturi flow cell for crystalloid solution and when blood is caused to flow through said at least one venturi flow cell for blood; and

,

means for self-venting of gases from said transducers comprising;

at least one second chamber;

at least one gas permeable membrane dividing said at least one second chamber into at least one upper cavity and at least one lower cavity;

at least one opening within said at least one upper cavity for self-venting gases to ambient;

at least one conduit means disposed between said at least one lower cavity of said at least one second chamber and said at least one first compartment of said at least one first chamber; and

,

at least one one-way valve disposed within said conduit means for passage of gases from said at least one first compartment of said at least one first chamber, through said at least one one-way valve into said at least one lower cavity of said at least one second chamber for self-venting through said at least one gas permeable membrane.

2. An assembly according to claim 1 further comprising:

a housing for securing said at least one venturi flow cell for crystalloid solution and said at least one venturi flow cell for blood and said at least one means for detecting a pressure drop.

3. An assembly for administering cardioplegia according to claim 1 wherein said at least one second chamber further comprises:

at least one cap member overlying said at least one conduit means within said at least one lower cavity of said second chamber;

at least one opening within said at least one cap member for passage of gas from said at least one conduit into said at least one lower cavity;

at least one top member having at least one cup member extending inwardly from said at least one top member into said at least one upper cavity;

at least one opening within said at least one cup member for self-venting gases from said at least one upper cavity to ambient;

at least one base member, said at least one gas permeable membrane separating said at least one top member from said at least one base member; and

,

a plurality of ribs on the interior surface of at least one of said at least one top member and said at least one base member.

4. An assembly according to claim 1 wherein at least one of said venturi flow cells and said transducers is made of a plastic.

5. An assembly according to claim 1 wherein:

said transducers have communication means for transmission of data to a microprocessor.

6. An assembly according to claim 5 wherein:

said means for communication with a microprocessor include separable connection means.

7. An assembly for cardioplegia delivery according to claim 1 wherein:

said at least one venturi flow cell for flow of blood or crystalline solution therethrough has a throat sized to ensure that a pressure drop across the throat is sufficient for detection by said at least one means for detecting a pressure drop.

8. An assembly for cardioplegia delivery according to claim 7 wherein:

said at least one venturi flow cell for flow of blood or crystalline solution therethrough is further sized to optimize flow of the blood or crystalline solution through the throat.