Solid contact ion-selective electrode

• US 5,840,168 A
• Filed: 06/16/1995
• Issued: 11/24/1998
• Est. Priority Date: 06/16/1995
• Status: Expired due to Fees

• Current Assignee: Orion Research, Inc. (Thermo Fisher Scientific Incorporated)
• Original Assignee: Orion Research, Inc. (Thermo Fisher Scientific Incorporated)
• Inventors: Chaniotakis, Nikolas A., West, Steven J.
• Primary Examiner(s): Bell, Bruce F.
• Application Number:
  US08/490,935
• Time in Patent Office: 1,257 Days
• Field of Search: 204/403, 204/416, 204/418, 204/435, 204/419, 204/294, 422/56, 422/82.03
• US Class Current: 204/416
• CPC Class Codes: G01N 27/3335 the membrane containing at least one organic component G01N27/3271 takes precedence; aspects concerning the enzyme reagent in enzyme electrodes C12Q1/001
• CPC Class Codes: G01N 27/4035 Combination of a single ion-sensing electrode and a single reference electrode G01N27/406 and G01N27/413 take precedence

Abstract

A new substrate for the construction of solid internal contact ion-selective electrode comprising a conductive and porous carbon matrix is described. The well-defined (i.e., fixed) interfacial potential between the organic electroactive phase and the internal reference element, coupled with the electrode'"'"'s very slow change from water activity at the internal reference element, supports the well-behaved and reproducible electrode operation. Solid contact sensors for two different ions were constructed, and their potentiometric behavior was compared with their symmetric counterparts. The potentiometric response was monitored over a period of one month with excellent results for drift, base line stability, response time, selectivity, and detection limit.

Claims

1. A solid contact ion-selective electrode comprising a substrate comprising a conductive and porous carbon matrix, wherein the interfacial potential of said electrode is fixed by the presence of a metal M and metal salt MX in said substrate, and wherein the presence of an aqueous layer is substantially eliminated, so that the electrode contains essentially no aqueous solution or air bubbles.

2. An electrode of claim 1, wherein the metal M is selected from the group consisting of silver, copper, lead, and mercury;

and wherein the anion X of the salt is selected from the group consisting of chloride, bromide, iodide, and perchlorate.

3. An electrode of claim 1 or 2, wherein the porous carbon substrate further comprises an organic phase containing ion carriers and hosts and wherein the hydrophobic nature of this organic phase inhibits penetration or permeation of water from an aqueous sample solution external to the electrode.

4. An electrode of claim 3, wherein the organic phase comprises the solvent bis(2-ethylhexyl)sebacate and the polymer poly(vinly chloride).

5. An electrode of claim 3, wherein the organic phase comprises the solvent ortho-nitrophenyl octyl ether.

6. An electrode of claim 3, wherein the ion carrier in the organic phase is selected from the group consisting of nickel-phenanthroline and tridodecylmethylammonium nitrate, thereby permitting the sensing of the ion nitrate.

7. An electrode of claim 3, wherein the ion carrier in the organic phase is valinomycin, thereby permitting the sensing of the ion potassium.