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Gastrointestinal drug delivery system

  • US 5,840,332 A
  • Filed: 01/18/1996
  • Issued: 11/24/1998
  • Est. Priority Date: 01/18/1996
  • Status: Expired due to Term
First Claim
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1. A drug delivery formulation for localized drug release in the gastrointestinal tract of an animal comprising:

  • a. a core comprising a drug and core material; and

    b. a coating surrounding said core, said coating having an outer surface,wherein said coating comprises water-insoluble hydrophilic particulate matter embedded in a water-insoluble carrier, such that when said formulation enters the gastrointestinal tract, said particulate matter absorbs liquid, thus forming channels that interconnect said core with said outer surface of said coating, and through which channels, said drug from said core is released into the gastrointestinal tract.

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