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Phenotypic characterization of the hematopoietic stem cell

  • US 5,840,580 A
  • Filed: 05/14/1997
  • Issued: 11/24/1998
  • Est. Priority Date: 05/01/1990
  • Status: Expired due to Term
First Claim
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1. A population of human cells that lacks mature progenitor cells of the erythroid, lymphoid, and myeloid lineages and is enriched for hematopoietic stem cells wherein said stem cells are capable of limited self-renewal and differentiation into erythroid myeloid and lymphoid progenitors and mature cells, which population is comprised of cells having a CD34+ /CD38- /HLA-DR+ phenotype, wherein cells having said phenotype comprise at least 95% of said population.

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