Image reconstruction from V-projections acquired by Compton camera

• US 5,841,141 A
• Filed: 06/03/1997
• Issued: 11/24/1998
• Est. Priority Date: 06/03/1997
• Status: Expired due to Fees

• Current Assignee: University of Utah (State of Utah)
• Original Assignee: University of Utah (State of Utah)
• Inventors: Basko, Roman, Zeng, Gengsheng Lawrence, Gullberg, Grant T.
• Primary Examiner(s): Hannaher, Constantine
• Application Number:
  US08/868,273
• Time in Patent Office: 539 Days
• Field of Search: 378/6, 378/87, 250/363.03, 250/363.04
• US Class Current: 250/363.04
• CPC Class Codes: A61B 6/037 Emission tomography
• CPC Class Codes: G01T 1/1642 using a scintillation crystal and position sensing photodetector arrays, e.g. ANGER cameras

Abstract

A SPECT system includes a Compton camera (14) disposed on a gantry (16). The camera (14) includes linear detectors (30a, 30b) operating without mechanical collimation for detecting radiation emanating from a subject to be imaged. A data processor (22) collects and processes radiation data in accordance with the detected radiation. Position and energy resolving circuitry (24) determines positions and energy deposited by photons striking the detectors. A projection generator (34) generates divergent projections or V-projections based on the collected data which determine a possible location of a gamma source of the detected radiation. A conversion processor (36) converts the V-projections into parallel projection data such as a Radon transformation. A reconstruction processor (38) reconstructs an image representation of a region of interest from the subject from the parallel projection data using filtered back projection. Alternately, two Compton cameras (70, 72) disposed at a selected angle to each other collect the radiation data and V-projections are generated from both cameras. A combination of V-projections are selected from both cameras and are converted into parallel projections before reconstruction of an image representation.

Claims

1. A method of generating an image representation of a region of interest of a subject having radiation emitted therefrom, the radiation being detected by a first Compton camera, the method comprising:

collecting radiation data from the detected radiation as a v-shaped projection defined by converging lines;

converting the v-shaped projection into a parallel projection; and

reconstructing an image representation from the parallel projection.

2. The method of generating an image representation as set forth in claim 1 further including:

providing at least first and second radiation detectors for collecting the radiation data, the first radiation detector being disposed between the subject and the second radiation detector and being parallel to the second radiation detector, the detected radiation undergoing Compton scattering in the first radiation detector;

determining detection positions of a photon detected on the first and second radiation detectors;

determining an energy deposited by the photon on both the first and second radiation detectors at the detection positions; and

determining the v-shaped projection based on the detection positions and the energy determined on both the first and second radiation detectors.

3. The method of generating an image representation as set forth in claim 1 further including providing a second Compton camera having a plurality of radiation detectors for collecting radiation data, the first and second Compton cameras being disposed at a fixed angle to each other and the subject being positioned so as to be viewed by both Compton cameras.

4. The method of generating an image representation as set forth in claim 3 further including:

generating v-shaped projections from the radiation data collected from both the first and second Compton cameras;

selecting a combination of the v-shaped projections from both the first and second Compton cameras where at least one v-shaped projection selected being generated from the first Compton camera and at least one v-shaped projection selected being generated from the second Compton camera; and

converting the selected v-shaped projections to parallel projections.

5. The method of generating an image representation as set forth in claim 1 further including:

providing three radiation detectors disposed in parallel to each other for detecting radiation emitted from the subject, the radiation exhibiting Compton scattering in at least one of the three radiation detectors and being absorbed in another of the three radiation detectors; and

collecting radiation data as the v-shaped projection based on corresponding radiation detected on each of the three radiation detectors.

6. The method of generating an image representation as set forth in claim 5 further includes reconstructing a three-dimensional image representation of a region of interest from the subject based on the v-shaped projection.

7. The method of generating an image representation as set forth in claim 1 wherein the converting includes converting the v-shaped projection into a Radon projection to obtain the parallel projection.

8. The method of generating an image representation as set forth in claim 1 wherein the reconstructing includes generating an image representation of the region of interest and a by-product image of the region of interest.

9. The method of generating an image representation as set forth in claim 8 further including deleting the by-product image.

10. The method of generating an image representation as set forth in claim 1 further including selectively rotating the Compton camera around the subject.

11. The method of generating an image representation as set forth in claim 1 further including:

collecting a plurality of v-shaped projections from the detected radiation; and

converting a selected subset of the plurality of v-shaped projections into parallel projections.

12. The method of generating an image representation as set forth in claim 1 wherein the reconstructing includes filtered back projection.

13. A diagnostic imaging system for reconstructing an image representation of a subject including a first plurality of radiation detectors parallelly disposed to each other for detecting radiation from an examination region, and producing electrical data indicative of coordinate locations and energy values on each of the radiation detectors at which radiation is detected, the radiation detected being scattered by at least one of the radiation detectors at a scattering angle, and a reconstruction processor reconstructs an image representation, the diagnostic imaging system comprising:

a projection processor for determining the scattering angle based on the energy values of the received radiation on the first plurality of radiation detectors and generating divergent projection data defined by (i) a vertex at a location where the radiation is detected on a first radiation detector of the first plurality of radiation detectors nearest the examination region, and (ii) the scattering angle; and

a conversion processor for converting the divergent projection data to parallel projection data which the reconstruction processor reconstructs into an image representation.

14. The diagnostic imaging system as set forth in claim 13 wherein the reconstruction processor reconstructs the image representation by filtered back projection.

15. The diagnostic imaging system as set forth in claim 13 wherein the projection processor defines two divergent semilines which converge at the vertex of the projection data forming an angle therebetween of twice the scattering angle, and the conversion processor includes a means for calculating integrals along the semilines to generate corresponding parallel projection data.

16. The diagnostic imaging system as set forth in claim 13 wherein the first plurality of radiation detectors include three radiation detector planes disposed in parallel to each other and the projection processor generates the divergent projection data based on the radiation detected on each of the three radiation detector planes.

17. The diagnostic imaging system as set forth in claim 16 wherein the reconstruction processor generates a three-dimensional image representation based on the divergent projection data generated from the radiation detected on each of the three radiation detector planes.

18. The diagnostic imaging system as set forth in claim 13 further including a second plurality of radiation detectors for detecting radiation from the examination region and producing electrical data indicative of coordinate locations and energy values on each of the second plurality of radiation detectors at which radiation is detected, the radiation detected being scattered by at least one of the second plurality of radiation detectors at a scattering angle, the second plurality of radiation detectors being disposed at a selected angle to the first plurality of radiation detectors, the projection processor generating second divergent projection data based on the radiation detected by the second plurality of radiation detectors.

19. The diagnostic imaging system as set forth in claim 18 wherein the conversion processor generates the parallel projection data from the divergent projection data from both the first and second pluralities of radiation detectors.

20. A method of generating an image representation of a region of interest of a subject by a SPECT diagnostic imaging system where the subject is injected with a radiation source, the method comprising:

detecting a photon from the radiation source at a first position on a first radiation detection plane and scattering the photon at a scattering angle;

detecting the scattered photon at a second position on a second radiation detection plane, the second radiation detector plane being parallel to the first radiation detection plane;

determining two lines which intersect at the first position on the first radiation detection plane which diverge in accordance with the scattering angle, a source of the photon lying along one of the lines;

generating a three-dimensional set of projection data based on integrals taken along the two lines;

dividing the three-dimensional set of projection data into a plurality of two-dimensional subsets of projection data such that one subset defines an equivalency with a line integral of the region of interest; and

reconstructing the one subset of projection data into an image representation of the region of interest of the subject.

21. The method of generating an image representation as set forth in claim 20 further including determining photon energy values at both the first and second positions.

22. The method of generating an image representation as set forth in claim 20 wherein the reconstructing includes reconstructing a desired image representation of the region of interest of the subject and a by-product, mirrored shear image of the desired image representation.

23. The method of generating an image representation as set forth in claim 20 wherein the generating projection data includes:

determining a plurality of integrals along the lines; and

combining the plurality of integrals to form the three-dimensional set of projection data.

24. The method of generating an image representation as set forth in claim 20 wherein the step of dividing the set of projection data includes generating an equivalent Radon transform of the projection data.

25. The method of generating an image representation as set forth in claim 20 further including:

detecting a second photon of radiation at a first position on a third radiation detection plane disposed at a right angle to the first radiation detection plane and scattering the photon;

detecting the scattered photon from the third radiation detection plane at a fourth radiation detection plane parallel to the third radiation detection plane; and

generating the three dimensional set of projection data based on the photons detected at the first, second, third and fourth radiation planes.

26. An image reconstruction assembly which generates an image representation of an object including a gamma source, the assembly comprising:

radiation detecting means for detecting radiation received from the gamma source by electronic collimation and collecting radiation data based on the radiation detected;

a means for generating divergent projection data from the radiation data collected;

a means for transforming the divergent projection data into parallel projection data; and

a reconstruction processor which reconstructs the parallel projection data into an image representation.

27. The image reconstruction assembly as set forth in claim 26 wherein the generating means generates the divergent projection data based on two lines forming a v-shape having a vertex on the radiation detecting means, the two lines being determined by locations of detected radiation by the radiation detecting means and energy deposited at the locations, the locations being related by a scatter angle, the two lines defining an area for locating the gamma source.

28. The image reconstruction assembly as set forth in claim 26 wherein the radiation detecting means includes a first, second, and third radiation detectors, the first detector being disposed nearest to the gamma source, the third detector being disposed furthest from the gamma source and the second detector being disposed between the first and third detectors such that a photon from the gamma source detected by the first radiation detector undergoes scattering in the first and second detectors and the third detector absorbing the photon.

29. The image reconstruction assembly as set forth in claim 26 wherein the radiation detecting means includes first and second Compton cameras disposed at a right angle to each other.