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Method for repairing cartilage

  • US 5,842,477 A
  • Filed: 02/21/1996
  • Issued: 12/01/1998
  • Est. Priority Date: 02/21/1996
  • Status: Expired due to Term
First Claim
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1. A method of producing cartilage at a cartilage defect site in vivo comprising:

  • (a) implanting into the defect site a biocompatible, non- living three-dimensional scaffold structure in combination with periosteal tissue, perichondrial tissue or a combination of said tissues; and

    (b) separately administering into the defect site a preparation of stromal cells for attachment to the scaffold in vivo and for inducing chondrogenesis or migration of stromal cells from the in vivo environment adjacent to the defect site to the scaffold.

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