Probe for thermal ablation

• US 5,843,075 A
• Filed: 02/06/1997
• Issued: 12/01/1998
• Est. Priority Date: 06/09/1995
• Status: Expired due to Fees

• Current Assignee: Engineering & Research Associates Inc. (Machine Solutions, Inc.)
• Original Assignee: Engineering & Research Associates Inc. (Machine Solutions, Inc.)
• Inventors: Taylor, Junius E.
• Primary Examiner(s): COHEN, LEE S
• Application Number:
  US08/796,227
• Time in Patent Office: 663 Days
• Field of Search: 606/41, 606/40, 606/49, 606/34, 606/38, 128/642, 128/696, 607/99, 607/100, 607/122, 600/374, 600/393
• US Class Current: 606/34
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00041 Heating, e.g. defrosting
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00738 Depth, e.g. depth of ablation
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00827 Current
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/00875 Resistance or impedance
• CPC Class Codes: A61B 2018/00892 Voltage
• CPC Class Codes: A61B 2018/124 switching the output to different electrodes, e.g. sequentially
• CPC Class Codes: A61B 2562/0217 Electrolyte containing
• CPC Class Codes: A61B 2562/043 in a linear array
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6855 with a distal curved tip
• CPC Class Codes: A61N 1/403 for thermotherapy, e.g. hyperthermia

Abstract

A probe for use with a catheter in an electrophysiological procedure to map and to ablate any of several tissue sites without repositioning the probe includes a metallic tip and a plurality of metallic rings, each tip and ring having a first work function and energized by a source of RF energy. The RF energy return path is through a further electrode of a metallic material having a second work function and disposed at a tissue location removed from the ablation site. After the sites have been mapped and one or more sites are selected for ablation, the selected site(s) is ablated prior to any repositioning of the probe. Regulation of the temperature at the ablation site(s) is achieved by sensing the temperature dependent current of a galvanic cell created by the tissue between the energized tip/ring and the further electrode due to their different work functions.

Claims

1. Apparatus for mapping tissue to locate a site to be ablated and for ablating the site located, said apparatus comprising in combination:

(a) a probe having a plurality of electrodes disposed therealong for placement adjacent the tissue to be mapped;

(b) a data acquisition circuit for performing mapping functions in response to signals generated by the tissue proximate at least one electrode of said plurality of electrodes to identify and locate a tissue site to be ablated;

(c) an RF generator for generating RF energy to ablate a located ablation site;

(d) a galvanic cell having tissue as an electrolyte and serving as a current source upon application of RF energy during ablation for producing an output signal reflective of the current generated;

(e) a switching circuit for selectively interconnecting said data acquisition circuit and said RF generator to each electrode of said plurality of electrodes;

(f) a plurality of conductors interconnecting said switching circuit with said plurality of electrodes; and

(g) a circuit responsive to the output signal of said galvanic cell for controlling the power generated by said RF generator and applied to the electrodes of said plurality of electrodes through said switching circuit.

2. The apparatus of claim 1 wherein said plurality of electrodes includes a plurality of rings disposed in spaced apart relationship along said probe capable of producing a continuous lesion at the ablation site as a function of the number of rings of said plurality of rings interconnected with said RF generator by said switching circuit.

3. The apparatus of claim 2 wherein said plurality of electrodes includes a tip electrode.

4. The apparatus of claim 3 wherein said switching circuit interconnects only one of the rings of said plurality of rings and said tip electrode whichever ring or tip corresponds with the site to be ablated.

5. The apparatus of claim 1 wherein said probe remains stationary adjacent the tissue after the mapping function performed has identified and located the site to be ablated and remains stationary during interconnection of said RF generator to ablate the located site.

6. The apparatus of claim 5 wherein said switching circuit interconnects only selected ones of the electrodes of said plurality of electrodes which correspond with the site to be ablated.

7. The apparatus of claim 1 wherein said switching circuit interconnects only selected ones of the electrodes of said plurality of electrodes which correspond with the site to be ablated.

8. Apparatus for mapping tissue to locate a site to be ablated and for ablating the site located, said apparatus comprising in combination:

(a) a probe having a plurality of electrodes disposed therealong for placement adjacent the tissue to be mapped;

(b) a further electrode adapted to be placed adjacent the tissue at a site remote from said probe;

(c) a data acquisition circuit for performing mapping functions in response to signals generated between the tissue proximate each electrode of said plurality of electrodes and said further electrode to identify and locate a tissue site to be ablated;

(d) an RF generator for generating RF energy to ablate a located ablation site;

(e) a galvanic cell formed by at least one electrode of said plurality of electrodes and said further electrode and having tissue as an electrolyte disposed therebetween and serving as a current source upon application of RF energy during ablation for producing an output signal reflective of the current generated;

(f) a switching circuit for selectively interconnecting said data acquisition circuit and said RF generator to at least a selected electrode of said plurality of electrodes and to said further electrode;

(g) a plurality of conductors interconnecting said switching circuit with said plurality of electrodes and said further electrode; and

(h) a circuit responsive to the output signal of the galvanic cell for controlling the power generated by said RF generator and applied to each electrode of said plurality of electrodes through said switching circuit.

9. The apparatus of claim 8 wherein said plurality of electrodes includes a plurality of rings disposed in spaced apart relationship along said probe.

10. The apparatus of claim 9 wherein said plurality of electrodes includes a tip electrode.

11. The apparatus of claim 10 wherein said switching circuit interconnects with only one ring of said plurality of rings or said tip electrode, whichever corresponds with the site to be ablated.

12. The apparatus of claim 8 wherein said probe remains stationary adjacent the tissue after the mapping function performed has identified and located the site to be ablated and remains stationary during operation of said RF generator to ablate the located site.

13. The apparatus of claim 12 wherein said switching circuit interconnects only the electrode of said plurality of electrodes which corresponds with the site to be ablated and said further electrode.

14. The apparatus of claim 8 wherein said switching circuit interconnects only the electrode of said plurality of electrodes which corresponds with the site to be ablated and said further electrode.