Dynamic bandwidth control in an implantable medical cardiac stimulator

• US 5,843,133 A
• Filed: 04/14/1997
• Issued: 12/01/1998
• Est. Priority Date: 04/14/1997
• Status: Expired due to Term

• Current Assignee: Intermedics Incorporated (Boston Scientific Corporation)
• Original Assignee: Sulzer Intermedics, Inc. (Sulzer AG)
• Inventors: Routh, Andre, Bruls, Annette, Woodson, Drury III, Vandegriff, Joseph, Verboven, Yves
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US08/843,236
• Time in Patent Office: 596 Days
• Field of Search: 607/27, 607/9, 607/14, 607/28, 607/30, 607/32, 600/515, 600/518
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: A61N 1/385 Devices for inducing an abnormal cardiac function, e.g. fibrillation
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

An implantable medical device for electrically stimulating the heart to beat includes a sense circuit for detecting cardiac electrical activity. The sense circuit includes a band pass filter with an adjustable frequency response. The frequency response can be repeatedly adjusted after implantation of the medical device and preferably is adjusted upon detection of the loss of normal sinus rhythm (NSR) in the heart'"'"'s atria. The loss of NSR often indicates atrial fibrillation (AF), and the filter'"'"'s frequency response is adjusted to increase the sensitivity of the sense circuit to the cardiac electrical activity typical during AF. The medical device is calibrated during implantation or at subsequent doctor visits with the aid of a calibration device external to the body. Cardiac electrical activity in the form of an electrogram is transmitted from the medical device to the external calibration device. The transmitted electrogram preferably includes both NSR and AF rhythms. The calibration device computes two sets of filter coefficients; one set for increased filter sensitivity during NSR and another set for increased sensitivity during AF. The coefficients are transmitted to the medical device which uses the appropriate set of coefficients to increase the filter'"'"'s frequency response during both NSR and AF.

Claims

1. A medical device for electrically stimulating the heart, comprising:

a logic and control unit for initiating a pacing pulse to be delivered to the heart;

an output multiplier/regulator coupled to said logic and control unit, said output multiplier/regulator receiving said pacing pulse from said logic and control unit and altering the magnitude of the pacing pulse;

a plurality of electrodes for coupling to the heart, said pacing pulse delivered to the heart through said electrodes; and

a sense circuit including a band pass filter which includes a dynamically adjustable frequency response, said frequency response is dynamically adjustable by an external device, said sense circuit providing to said logic and control unit an electrical signal indicative of electrical activity in a predetermined chamber of the heart;

said logic and control unit provides different modes of pacing and switches modes depending upon predetermined conditions, and wherein said dynamically adjustable frequency response of said band pass filter is adjusted upon a mode switch.

2. The medical device of claim 1 wherein said logic and control unit provides different modes of pacing and switches modes depending upon predetermined conditions, and wherein said dynamically adjustable frequency response of said band pass filter is adjusted in response to a control signal from said logic and control unit.

3. The medical device of claim 1 wherein said frequency response of said dynamically adjustable band pass filter is adjusted upon a mode switch to increase said medical device'"'"'s sensitivity to atrial fibrillation.

4. The medical device of claim 1 wherein said medical device includes memory for storing filter coefficients for determining the frequency response of said dynamically adjustable band pass filter.

5. The medical device of claim 1 wherein said dynamically adjustable band pass filter comprises a switched capacitor filter.

6. The medical device of claim 5 wherein said control signal from said logic and control unit is a clock signal.

7. The medical device of claim 6 wherein said dynamically adjusted frequency response is determined by said clock signal.

8. The medical device of claim 7 wherein said dynamically adjusted frequency response is adjusted by changing the frequency of said clock signal.

9. The medical device of claim 8 wherein said logic and control unit adjusts the frequency response of said band pass filter by adjusting the frequency of said clock signal.

10. A method for calibrating an implantable pacemaker having a dynamically adjustable band pass filter, said method using an external calibration device and comprising the steps of:

(a) transmitting an electrogram waveform to said calibration device;

(b) performing a frequency analysis on said electrogram waveform with said calibration device;

(c) determining a frequency response suitably sensitive to said electrogram;

(d) determining filter coefficients for implementing said frequency response; and

(e) transmitting said filter coefficients from said calibration device to said implantable pacemaker.

11. The method of claim 10 wherein said transmitted electrogram in step (a) includes normal sinus rhythm.

12. The method of claim 10 wherein said transmitted electrogram in step (a) includes atrial fibrillation.

13. The method of claim 10 further including the steps of inducing atrial fibrillation and obtaining an electrogram including said atrial fibrillation before performing step (a).

14. A method for calibrating an implantable pacemaker having a dynamically adjustable band pass filter said method using an external calibration device and comprising the steps of:

(a) detecting atrial fibrillation;

(b) storing a sample of an atrial electrogram including said detected atrial fibrillation in a memory device in said pacemaker;

(c) determining a first frequency response and a second frequency response for said dynamically adjustable band pass filter wherein said first frequency response is suitably sensitive for normal sinus rhythm and said second frequency response is suitably sensitive for atrial fibrillation.

15. The method of claim 14 wherein said step of determining a first and a second frequency response (step c) includes the steps of:

(c)(1) transmitting a first electrogram waveform to said calibration device, said first electrogram including normal sinus rhythm;

(c)(2) transmitting a second electrogram waveform to said calibration device, said second electrogram including atrial fibrillation; and

(c)(3) performing a frequency analysis on said first and said second electrograms.

16. The method of claim 15 further including the step of:

(c)(4) determining said first frequency response suitably sensitive to said first electrogram;

(c)(5) determining a first set of filter coefficients for providing said first frequency response;

(c)(6) determining said second frequency response suitably sensitive to said second electrogram;

(c)(7) determining a second set of filter coefficients for providing said second frequency response; and

(c)(8) transmitting said first and said second sets of filter coefficients from said calibration device to said implantable pacemaker.

17. A method for electrically stimulating a heart using an implantable pacemaker that includes a pacing circuit, a sense circuit including a dynamically adjustable band pass filter, and a logic and control unit, comprising the steps of:

(a) operating said pacemaker in a first pacing mode with said band pass filter set to a first frequency response;

(b) monitoring an electrogram;

(c) switching said pacemaker to a second pacing mode upon detection of a first event in the electrogram; and

(d) increasing the sensitivity of the sense circuit to said electrogram upon mode switching.

18. The method of claim 17 further including the steps of:

(e) switching said pacemaker to said first pacing mode upon detection of a second event in said electrogram; and

(f) changing the frequency response of said band pass filter to said first frequency response.

19. The method of claim 18 wherein said first event includes atrial fibrillation.

20. The method of claim 19 wherein said second event includes normal sinus rhythm.

21. The method of claim 17 wherein step (d) comprises the step of setting said band pass filter to a second frequency response that is lower than said first frequency response.

22. A medical system for monitoring the heart, comprising:

an implantable medical device including a processor coupling together an atrial sense circuit having a dynamically adjustable band pass filter and a telemetry unit; and

an external calibration device adapted to communicate to the implantable medical device;

wherein said telemetry unit transmits atrial electrogram data to said calibration device; and

wherein said calibration device determines a set of filter coefficients for dynamically adjusting said dynamically adjustable band pass filter to provide a frequency response that increases the medical device'"'"'s sensitivity to said transmitted atrial electrogram data.

23. The medical system of claim 22 wherein said set of filter coefficients is transmitted to said medical device through said telemetry unit.

24. The medical system of claim 23 wherein said medical device includes memory for storing said filter coefficients.