System and method for treating select tissue in a living being

• US 5,845,646 A
• Filed: 11/05/1996
• Issued: 12/08/1998
• Est. Priority Date: 11/05/1996
• Status: Expired due to Term

• Current Assignee: Jerome H. Lemelson
• Original Assignee: Jerome H. Lemelson
• Inventors: Lemelson, Jerome
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): MANTIS MERCADER, ELENI M
• Application Number:
  US08/743,794
• Time in Patent Office: 763 Days
• Field of Search: 128/653.1, 128/653.2, 128/721, 128/897, 128/898, 128/899, 128/665, 378/41, 378/42, 378/62, 378/63, 604/164, 604/93, 604/264, 604/280, 604/21, 604/281, 604/95, 252/500, 285/261, 600/407, 600/410
• US Class Current: 128/899
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2010/045 Needles pointed biopsy devices with vacuum aspiration A61B10/0283
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2017/22077 with a part piercing the tissue A61B2017/22044 takes precedence
• CPC Class Codes: A61B 2017/320004 abrasive
• CPC Class Codes: A61B 2090/3614 using optical fibre
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/0089 Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/0082 Catheter tip comprising a tool
• CPC Class Codes: A61M 25/0084 being one or more injection needles
• CPC Class Codes: A61M 25/0138 having flexible regions as a result of weakened outer material, e.g. slots, slits, cuts, joints or coils
• CPC Class Codes: A61M 25/0147 with movable mechanical means, e.g. pull wires
• CPC Class Codes: A61M 25/0158 with magnetic or electrical means, e.g. by using piezo materials, electroactive polymers, magnetic materials or by heating of shape memory materials

Abstract

A catheter suitable for directing a measured aliquot of liquid drug to a specific target location in the body having a reservoir containing a premeasured aliquot of liquid drug which is positioned near the end of catheter. The reservoir is attached to the distal end of an extendable member, which is used to extend the hollow needle into the tissue surrounding the distal end of the catheter through an orifice.

Claims

1. A drug delivery system comprising:

a. a catheter with an exterior surface, a proximal end and a distal end and having at least one lumen with an opening at said distal end of said catheter;

b. a drug reservoir having a proximal end and a distal end situated inside said lumen adjacent said distal end of said catheter;

c. an extendable member connected to said proximal end of said reservoir;

d. a hollow tube connected to said distal end of said reservoir and communicating therewith, having a dispensing front end with an opening therein, a hollow needle being completely disposed and supported within said lumen and movable generally longitudinally through said lumen from a retracted position therein whereby the dispensing end of said tube does not protrude beyond the exterior surface of the catheter, to an extended position whereby said dispensing end of said needle protrudes through said opening beyond the exterior surface of the catheter so as to permit said dispensing end of said needle to penetrate tissue positioned against or in close proximity to the exterior surface of said catheter;

e. a force means for controllably moving said extendable member in a longitudinal direction to extend said needle;

f. a dispensing mechanism contained within said reservoir; and

g. release means for remotely power operating or triggering said dispensing mechanism.

2. The drug delivery system of claim 1, wherein said dispensing mechanism comprises a spring-loaded piston.

3. The drug delivery system of claim 2, further comprising a rupture disk situated inside said hollow needle.

4. The drug delivery system of claim 1 wherein said release means comprises a catch operated by rotating said extendable member.

5. The drug delivery system of claim 1, further comprising at least one pull wire for steering said catheter.

6. The drug delivery system of claim 1, wherein said dispensing mechanism comprises a motor-operated piston.

7. The drug delivery system of claim 1, wherein said dispensing mechanism further comprises:

(a) a rotatable cylindrical housing containing a plurality of reservoirs;

(b) an axle around which said cylindrical housing revolves; and

(c) means for revolving said cylindrical housing to align said reservoirs with said hollow needle.

8. The drug delivery system of claim 7, wherein said means for revolving said housing is a pull wire wound around said housing.