Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6) and uses thereof

• US 5,854,398 A
• Filed: 11/13/1996
• Issued: 12/29/1998
• Est. Priority Date: 07/25/1996
• Status: Expired due to Term

• Current Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Original Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Inventors: Moore, Patrick S., Chang, Yuan, Bohenzky, Roy A., Russo, James J., Edelman, Isidore S.
• Primary Examiner(s): Stucker, Jeffrey
• Assistant Examiner(s): Bui, Phuong T.
• Application Number:
  US08/748,640
• Time in Patent Office: 776 Days
• Field of Search: 424/141.1, 424/147.1, 424/159.1, 424/186.1, 424/229.1, 435/7.1, 435/69.3, 436/548, 530/387.1-388.1, 530/388.3, 530/389.1, 536/23.72
• US Class Current: 530/387.1
• CPC Class Codes: A61K 39/00 Medicinal preparations containing antigens or antibodies materials for immunoassay G01N33/53
• CPC Class Codes: C07K 14/005 from viruses
• CPC Class Codes: C12N 2710/16422 New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

This invention provides an antibody specific to the peptide of KSHVIL-6.

Claims

1. An antibody specifically immunoreactive with Kaposi'"'"'s sarcoma-associated herpesvirus interleukin 6 having the amino acid sequence as set forth in SEQ ID NO:

1.

2. The antibody of claim 1, wherein said antibody is a polyclonal antibody.

3. The antibody of claim 2 raised against an immunogen comprising the polypeptides set forth in SEQ ID NO:

2 and SEQ ID NO;

3.

4. The antibody of claim 1, wherein said antibody is a monoclonal antibody.