Methods and compositions for topical treatment of ectoparasites
First Claim
1. A method for the topical treatment of ectoparasites on animal animal skin comprising the steps ofA) applying to the skin containing ectoparasites a water-soluble or water-dispersible, substantially air-impermeable liquid composition, wherein the liquid composition can range from free-flowing to viscous, and wherein the liquid composition contains at least one skin compatible surface active agent selected from the group consisting of(a) water-soluble or dispersible synthetic anionic surfactants selected from(i) anionic surfactants containing an organic hydrophobic group of 8 to 26 carbon atoms and at least one water-solubilizing group selected from sulfonate, sulfate, carboxylate, phosphonate and phosphate groups,(ii) C8 -C18 acyl sarcosinates,(iii) sodium and potassium salts of the reaction product of higher fatty acids containing 8-18 carbon atoms in the molecule esterified with isethionic acid,(iv) sodium and potassium salts of the C8 -C18 acyl N-methyl taurides,(v) sodium, potassium and ammonium alkyl phosphate esters, and(vi) sodium, potassium and ammonium akyl phosphate esters containing one to about 40 moles of ethylene oxide;
- (b) water soluble or dispersible nonionic surfactants selected from(i) the condensation product of an organic alphatic or alkyl aromatic hydrophobic compound having a carboxy, hydroxy, amido, or amino group with a free hydrogen attached to the nitrogen, and hydrophilic ethylene oxide groups,(ii) an aliphatic monhydric alcohol containing from 1-8 carbon atoms to which is attached a chain of oxyethylene and oxypropylene groups,(iii) a surfactant derived from the condensation of ethylene oxide with the product resulting from the reaction of propylenc oxide and ethylene diamine, and(iv) alkyl saccharide surfactants;
(c) water-soluble or dispersible cationic sutfactanlts selected from surfactants containing an organic hydrophobic group and a cationic solubilizing group;
(d) water-soluble or dispersible ampiphoteric surfactants which are salts of derivatives of aliphatic amines containing at least one cationic group;
(e) a water-soluble or dispersible zwitterionic surfactant selected from betaines and sulfobetaines;
(f) a water-soluble or dispersible polar nonionic surfactant in which a hydrophilic group contains a semi-polar bond directly between two atoms but wherein the surfactant molecule bears no net charge and does not dissociate into ions; and
(g) a soap which is an alkali metal, ammonium or alkanolammonium salt of a long chain fatty acid;
B) leaving the composition in contact with the skin until the ectoparasites have been killed; and
C) removing the composition and the dead ectoparasites from the skin.
6 Assignments
0 Petitions
Accused Products
Abstract
Methods and compositions for the topical treatment of ectoparasites on animal skin utilizing a water-soluble or water-dispersible, substantially air-impermeable liquid composition.
71 Citations
15 Claims
-
1. A method for the topical treatment of ectoparasites on animal animal skin comprising the steps of
A) applying to the skin containing ectoparasites a water-soluble or water-dispersible, substantially air-impermeable liquid composition, wherein the liquid composition can range from free-flowing to viscous, and wherein the liquid composition contains at least one skin compatible surface active agent selected from the group consisting of (a) water-soluble or dispersible synthetic anionic surfactants selected from (i) anionic surfactants containing an organic hydrophobic group of 8 to 26 carbon atoms and at least one water-solubilizing group selected from sulfonate, sulfate, carboxylate, phosphonate and phosphate groups, (ii) C8 -C18 acyl sarcosinates, (iii) sodium and potassium salts of the reaction product of higher fatty acids containing 8-18 carbon atoms in the molecule esterified with isethionic acid, (iv) sodium and potassium salts of the C8 -C18 acyl N-methyl taurides, (v) sodium, potassium and ammonium alkyl phosphate esters, and (vi) sodium, potassium and ammonium akyl phosphate esters containing one to about 40 moles of ethylene oxide; -
(b) water soluble or dispersible nonionic surfactants selected from (i) the condensation product of an organic alphatic or alkyl aromatic hydrophobic compound having a carboxy, hydroxy, amido, or amino group with a free hydrogen attached to the nitrogen, and hydrophilic ethylene oxide groups, (ii) an aliphatic monhydric alcohol containing from 1-8 carbon atoms to which is attached a chain of oxyethylene and oxypropylene groups, (iii) a surfactant derived from the condensation of ethylene oxide with the product resulting from the reaction of propylenc oxide and ethylene diamine, and (iv) alkyl saccharide surfactants; (c) water-soluble or dispersible cationic sutfactanlts selected from surfactants containing an organic hydrophobic group and a cationic solubilizing group; (d) water-soluble or dispersible ampiphoteric surfactants which are salts of derivatives of aliphatic amines containing at least one cationic group; (e) a water-soluble or dispersible zwitterionic surfactant selected from betaines and sulfobetaines; (f) a water-soluble or dispersible polar nonionic surfactant in which a hydrophilic group contains a semi-polar bond directly between two atoms but wherein the surfactant molecule bears no net charge and does not dissociate into ions; and (g) a soap which is an alkali metal, ammonium or alkanolammonium salt of a long chain fatty acid; B) leaving the composition in contact with the skin until the ectoparasites have been killed; and C) removing the composition and the dead ectoparasites from the skin. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
-
-
9. A method for the topical treatment of human scalp infected with head lice comprising the steps of
A) applying to the scalp containing head lice a water-soluble or water-dispersible, substantially air-impermeable liquid composition, wherein the liquid composition can range from free-flowing to viscous, and wherein the liquid composition contains at least one skin compatible surface active agent selected from the group consisting of (a) water-soluble or dispersible synthetic anionic sufactants selected from (i) anionic sufactants containing an organic hydrophobic group of 8 to 26 carbon atoms and at least one water-solublizing group selected from sulfonate, sulfate, carboxylate, phosphonate and phosphate groups, (ii) C8 -C18 acyl sarcosinates, (iii) sodium and potassium salts of the reaction product of higher fatty acids containing 8-18 carbon atoms in the molecule esterified with isethionic acid, (iv) sodium and potassium salts of the C8 -C18 acyl N-methyl taurides, (v) sodium, potassium and ammonium alkyl phosphate esters, and (vi) sodium, potassium and ammonium alkyl phosphate esters containing one to about 40 moles of ethylene oxide; -
(b) water-soluble or dispersible nonionic surfactants selected from (i) the condensation product of an organic aliphatic or alkyl aromatic hydrophobic compound having a carboxy, hydroxy, amido, or amino group with a free hydrogen attached to the nitrogen, and hydrophilic ethylene oxide groups, (ii) an aliphatic monohydric alcohol containing from 1-8 carbon atoms to which is attached a chain of oxyethylene and oxypropylene groups, (iii) a surfactant derived from the condensation of ethylene oxide with the product resulting from the reaction of propylene oxide and ethylene diamine, and (iv) alkyl saccharide surfactants; (c) water-soluble or dispersible cationic surfactants selected from surfactants having an organic hydrophobic group and a cationic solubilizing group; (d) water-soluble or dispersible amphoteric surfactants which are salts of derivatives of aliphatic amines containing at least one cationic group; (e) a water-soluble or dispersible zwitterionic surfactant selected from betaines and sulfobetaines; (f) a water soluble or dispersible polar nonionic surfactant in which a hydrophilic group contains a semi-polar bond directly between two atoms but wherein the surfactant molecule bears no net charge and does not dissociate into ions; and (g) a soap which is an alkali metal, ammonium or alkanolammonium salt of a long chain fatty acid; B) leaving the composition in contact with the scalp until the head lice have been killed; C) removing the composition and the dead head lice from the scalp. - View Dependent Claims (10)
-
-
11. A composition for the treatment of ectoparasites and their nits on animal skin comprising
I) a water-soluble or water-dispersible, substantially air-impermeable liquid composition, wherein the liquid composition can range from free-flowing to viscous, and wherein the liquid composition contains at least one skin compatible surface active agent selected from the group consisting of (a) water-soluble or dispersible synthetic anionic surfactants selected from (i) anionic surfactants containing an organic hydrophobic group of 8 to 26 carbon atoms and at least one water-solubilizing group selected from sulfonate, sulfate, caraboxylate, phosphonate and phosphate groups, (ii) C8 -C18 acyl sarcosinates, (iii) sodium and potassium salts of the reaction product of higher fatty acids containing 8-18 carbon atoms in the molecule esterified with isethionic acid, (iv) sodium and potassium salts of the C8 -C18 acyl N-methyl taurides, (v) sodium, potassium and ammonium alkyl phosphate esters, and (vi) sodium, potassium and ammonium alkyl phosphate esters containing one to about 40 moles of ethylene oxide; -
(b) water-soluble or dispersible nonionic surfactants selected from (i) the condensation product of an organic aliphatic or alkyl aromatic hydrophobic compound having a carboxy, hydroxy, amido,or amino group with a free hydrogen attached to the nitrogen, and hydrophilic ethylene oxide groups, (ii) an aliphatic monohydric alcohol containing from 1 to 8 carbon atoms to which is attached a chain of oxethylene and oxypropylene groups, (iii) a surfactant derived from the condensation of ethylene oxide with the product resulting from the reaction of propylene oxide and ethylene diamine, and (iv) alkyl saccharide surfactants; (c) water-soluble or dispersible cationic surfactants selected from surfactants containing an organic hydrophobic group and a cationic solubilizing group; (d) water-soluble or dispersible amphoteric surfactants which are salts of derivatives of aliphatic amines containing at least one cationic group; (e) a water-soluble or dispersible zwitterionic surfactant selected from betaines and sulfobetaines; (f) a water-soluble or dispersible polar nonionic surfactant in which a hydrophilic group contains a semi-polar bond directly between two atoms but wherein the surfactant molecule bears no net charge and does not dissociate into ions; and (g) a soap which is an alkali metal, ammonium or alkanolammonium salt of a long chain fatty acid; and II) an effective quantity of at least one enzyme that removes nits from skin and hair by loosening the nits from the skin and hair. - View Dependent Claims (12, 13, 14, 15)
-
Specification