Long acting GI and esophageal protectant
First Claim
Patent Images
1. A medicated chewing gum composition, which comprises:
- a) a gum base in an amount sufficient to form a chewing gum composition;
b) effective amounts of chewing gum additives to soften the gum base; and
c) an effective amount of an active pharmaceutical composition dispersed within a water-in-oil emulsion system having at least two phases, one phase comprises from about 75 to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about 1% by volume of an external hydrophobic phase, wherein the external hydrophobic phase is comprised of two components, one component being about 3 to about 97% of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than 10.
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Abstract
A bioadherent, orally ingestible system, which comprises: a water-in-oil emulsion system having at least two phases, one phase comprises from about 75% to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about 1% by volume of an external hydrophobic phase, wherein the external hydrophobic phase comprises two components, one component being about 3% to about 97% by volume of the hydrophobic phase of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than about 10.
33 Citations
31 Claims
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1. A medicated chewing gum composition, which comprises:
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a) a gum base in an amount sufficient to form a chewing gum composition; b) effective amounts of chewing gum additives to soften the gum base; and c) an effective amount of an active pharmaceutical composition dispersed within a water-in-oil emulsion system having at least two phases, one phase comprises from about 75 to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about 1% by volume of an external hydrophobic phase, wherein the external hydrophobic phase is comprised of two components, one component being about 3 to about 97% of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than 10. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A medicated confectionery composition, which comprises:
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a) a confectionery composition; and b) an effective amount of an active pharmaceutical composition dispersed with a water-in-oil emulsion system having at least two phases, one phase comprises from about 75 to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about 1% by volume of an external hydrophobic phase, wherein the external hydrophobic phase is comprised of two components, one component being about 3 to about 97% of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than 10. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification