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Method of inhibiting phagocytosis

  • US 5,858,981 A
  • Filed: 06/07/1996
  • Issued: 01/12/1999
  • Est. Priority Date: 09/30/1993
  • Status: Expired due to Term
First Claim
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1. A method of inhibiting the signal transduction of the γ

  • subunit of the IgE receptor Fcε

    RI comprising introducing into lung cells of a mammal bearing said receptor a peptide inhibitor of Syk kinase, or a mimetic of said peptide, wherein said peptide comprises the sequence YXXL (SEQ ID NO;

    8), wherein XX represents any two amino acids,said introduction being effected under conditions such that said signal transduction is inhibited.

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