Apparatus and method for measuring the variability of cardiovascular parameters

• US 5,862,805 A
• Filed: 11/06/1996
• Issued: 01/26/1999
• Est. Priority Date: 11/16/1995
• Status: Expired due to Term

• Current Assignee: Optelmed Limited
• Original Assignee: Optelmed Limited
• Inventors: Nitzan, Meir
• Primary Examiner(s): Yu, Mickey
• Assistant Examiner(s): CAMPEN, KELLY SCAGGS
• Application Number:
  US08/744,816
• Time in Patent Office: 811 Days
• Field of Search: 128/666, 128/667, 128/898, 600/481, 600/480, 600/485, 600/479, 600/507
• US Class Current: 128/898
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence

Abstract

Apparatus for measuring the variability of cardiovascular parameters, having a photoplethysmographic (PPG) probe, including a modulated first light source and a photodetector, a demodulator connected to the photodetector for demodulating PPG signals detected by the photodetector, an analog to digital converter for digitizing the demodulated signals, and a processor for repeatedly analysing the PPG signals for a predetermined number of times. A method for measuring the variability of cardovascular parameters.

Claims

1. A method for measuring variability of cardiovascular parameters, comprising:

performing a series of photoplethsymographic measurement on a patient over a predetermined period of time;

selecting parameters to be analyzed from the group of parameters consisting of;

the blood volume (BV) of the measured tissue;

the amplitude (AM) of the systolic increase in the blood volume of the tissue and the time duration (T) between the maxima of two adjacent photoplethsymographic pulses and the maximal rate of increase (Vmax) of the blood volume, and measuring the standard deviation of any selected parameter from said parameters.

2. The method as claimed in claim 1, further comprising performing correlation between the values of a selected parameter of two different sites on the body of said patient.

3. The method as claimed in claim 2, wherein said correlation is performed for each selected parameter P by the formula

4. A method as claimed in claim 1, further comprising the step of displaying curves depicting variations of the selected parameters as a function of time.