Polymeric microbeads
First Claim
1. Porous crosslinked polymeric microbeads having cavities joined by interconnecting pores wherein at least some of the cavities at the interior of each microbead communicate with the surface of the microbead and wherein approximately 10% of the microbeads are substantially spherical or substantially ellipsoidal or a combination thereof and the microbeads have an average void volume in the range of about 70% to about 98%.
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Abstract
The present invention relates to porous crosslinked polymeric microbeads having cavities joined by interconnecting pores wherein at least some of the cavities at the interior of each microbead communicate with the surface of the microbead. The present invention also relates to a process for producing a porous, crosslinked polymeric microbead as well as the product of this process. This process involves combining an oil phase with an aqueous discontinuous phase to form an emulsion, adding the emulsion to an aqueous suspension medium to form an oil-in-water suspension of dispersed emulsion droplets, and polymerizing the emulsion droplets to form microbeads. At least 10% of the microbeads produced in accordance with the present invention are substantially spherical or substantially ellipsoidal or a combination of the two.
165 Citations
41 Claims
- 1. Porous crosslinked polymeric microbeads having cavities joined by interconnecting pores wherein at least some of the cavities at the interior of each microbead communicate with the surface of the microbead and wherein approximately 10% of the microbeads are substantially spherical or substantially ellipsoidal or a combination thereof and the microbeads have an average void volume in the range of about 70% to about 98%.
Specification