System and method of operating a centrifuge utilizing a protocol record database

• US 5,865,718 A
• Filed: 01/27/1997
• Issued: 02/02/1999
• Est. Priority Date: 01/27/1997
• Status: Expired due to Term

• Current Assignee: Beckman Coulter Incorporated (Danaher Corporation)
• Original Assignee: Beckman Instruments, Inc. (Danaher Corporation)
• Inventors: Chan, Wan S.
• Primary Examiner(s): Cooley, Charles E.
• Application Number:
  US08/788,410
• Time in Patent Office: 736 Days
• Field of Search: 494/1, 494/7, 494/10, 494/11, 494/16, 494/20, 494/37, 494/85, 210/739, 210/767, 210/781, 210/782, 210/787, 210/85, 210/143, 210/138, 210/360.1, 364/502, 364/528.08
• US Class Current: 494/10
• CPC Class Codes: B04B 13/00 Control arrangements specially designed for centrifuges; Programme control of centrifuges control arrangements for feed, charge, or discharge B04B11/00
• CPC Class Codes: B04B 5/10 Centrifuges combined with other apparatus, e.g. electrostatic separators; Sets or systems of several centrifuges B04B5/12 takes precedence; magnetic or electrostatic separators B03C; amassing particles by electric fields, e.g. by agglomeration B03C3/0175

Abstract

A protocol record database is used in conjunction with operating a centrifuge device. Each protocol record includes information relevant to the centrifugation of a certain specimen. The user can search the database for a protocol on the basis of the specimen and/or the type of separation desired. The database has an interface to one or more centrifuges via a controller. The controller, operates a centrifuge in accordance with the run program of a selected protocol record. In a preferred embodiment, the protocol records have links to additional files which supplement the information contained in the protocol records. These supplemental files include information related to the availability and compatibility of the various hardware needed to perform a centrifugation. The supplemental files can also be used to provide general information to assist the user in setting up a centrifuge for an experiment.

Claims

1. A centrifuge system comprising:

a centrifuge device;

a data store for storing centrifugation protocols;

means for creating said centrifugation protocols and for storing said centrifugation protocols onto said data store;

display means for showing available protocols and for selecting one of said centrifugation protocols from said data store; and

controller means for operating said centrifuge device, including means for accessing said data store to obtain one of said centrifugation protocols and means for communicating a selected one of said centrifugation protocols to said centrifuge device;

whereby said centrifuge device is operated by said controller means in accordance with said selected one of said centrifugation protocols.

2. The centrifuge system of claim 1 wherein each of said centrifugation protocols is associated with a biochemical specimen, and said each centrifugation protocol includes a sample field which identifies said biochemical specimen, a first plurality of data fields which specify physical parameters of said biochemical specimen, a second plurality of data fields which identify hardware used to centrifuge said biochemical specimen and a third plurality of data fields which specify a run program for centrifugation of said biochemical specimen.

3. The centrifuge system of claim 2 wherein said display means includes means for specifying a biochemical specimen and physical parameters of said biochemical specimen, said display means further including search means for finding, in response to said means for specifying, a matching centrifugation protocol in said data store.

4. The centrifuge system of claim 1 further including a second data store having multimedia files and means for presenting said multimedia files to a user, said multimedia files containing information related to said centrifuge device and information related to hardware for use with said centrifuge device, each of said centrifugation protocols having one or more links to said multimedia files.

5. The centrifuge system of claim 1 further including at least a second centrifuge device, and said controller means further including means for selectively communicating with said centrifuge device and said second centrifuge device.

6. The centrifuge system of claim 1 further including means for communicating over a wide area network to access a remote data store, means for downloading additional centrifugation protocols stored in said remote data store and means for storing downloaded copies of said additional centrifugation protocols into said data store.

7. A method for centrifuging biochemical specimens comprising the steps of:

creating a database of protocol records, each protocol record having a first identifier which identifies a biochemical specimen, a second identifier which specifies a separation method, first parameters which specify physical attributes of said biochemical specimen, second parameters which specify hardware used to centrifuge said biochemical specimen and third parameters which specify a run program for centrifuging said biochemical specimen;

storing a plurality of said protocol records, including querying a user for information relating to a new protocol record, ensuring internal consistency of information provided by said user and recording said information as one of said protocol records in said database;

identifying a protocol record from among said plurality of protocol records; and

operating a centrifuge in accordance with said identified protocol record, including accessing said database to retrieve said run program associated with said identified protocol record and communicating said run program to said centrifuge.

8. The method of claim 7 wherein said step of storing further includes communicating over a wide area network, gaining access to a remote database and downloading an additional protocol record from said remote database.

9. The method of claim 7 wherein said step of storing further includes selecting audio-visual files related to hardware associated with a protocol record and linking selected audio-visual files to said protocol records.

10. The method of claim 9 wherein said step of identifying a protocol record includes displaying audio-visual information related to hardware used to centrifuge said specified biochemical specimen.

11. The method of claim 7 wherein said step of identifying a protocol record includes specifying a biochemical specimen and a separation method.

12. The method of claim 11 wherein said step of identifying a protocol record further includes specifying one or more physical attributes of said biochemical specimen.

13. The method of claim 7 wherein said step of operating a centrifuge further includes selecting between at least a first and a second centrifuge.

14. A system for centrifugation of samples, said system comprising:

a plurality of centrifuge devices;

a database of protocol records, each protocol record having fields which identify a sample, physical parameters of said sample, a centrifuge for centrifugation of said sample, hardware to be used with said centrifuge, centrifugation criteria and a run program for centrifugation of said sample;

a database of multimedia files, said multimedia files having information relating to said centrifuge devices and hardware for use with said centrifuge devices;

means for creating a new protocol record and for storing said new protocol record in said database of protocol records, including means for linking at least one of said multimedia files to said new protocol record;

means for selecting one of said protocol records, including means for identifying a sample and physical parameters of said identified sample and means for examining said multimedia files; and

means for controlling said centrifuge devices, including means for accessing said database of protocol records to obtain a run program of a selected protocol record and means for selectively communicating with one of said centrifuge devices, whereby a corresponding centrifuge device identified by said selected protocol record is controlled in accordance with a corresponding run program identified by said selected protocol record.

15. The system of claim 14 wherein said database of protocol records, said means for creating, said means for selecting and said means for controlling are computer programs executing on a computer.

16. The system of claim 14 further including a first computer having said database of protocol records, a second computer having said means for selecting and said means for controlling, said first and second computers having a communication link therebetween.

17. The system of claim 16 further including a third computer having said means for selecting and said means for controlling, said first and third computers having a communication link therebetween.

18. The system of claim 14 further including means for communicating over the Internet, means for obtaining protocol records from remote sites on the Internet and means for storing said obtained protocol records in said database of protocol records.

19. The system of claim 14 wherein said hardware includes rotors, centrifuge tubes and adapters.