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Stabilized naloxone formulations

  • US 5,866,154 A
  • Filed: 06/25/1996
  • Issued: 02/02/1999
  • Est. Priority Date: 10/07/1994
  • Status: Expired due to Fees
First Claim
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1. A parenteral pharmaceutical composition autoclaved for sterilization, wherein the pH is about 3.0-3.5, comprising:

  • a) an effective amount of 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one;

    b) a suitable acidic or buffer component;

    c) a stabilizing agent; and

    d) a tonicity adjusting agent.

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