Silicone composite vascular graft

• US 5,866,217 A
• Filed: 11/04/1991
• Issued: 02/02/1999
• Est. Priority Date: 11/04/1991
• Status: Expired due to Fees

• Current Assignee: Medrad Incorporated (Bayer AG)
• Original Assignee: Possis Medical, Inc. (Bayer AG)
• Inventors: Stenoien, Mark D., Scott, Robert J., Jenson, Mark L., Drasler, William J.
• Primary Examiner(s): RAIMUND, CHRISTOPHER W
• Application Number:
  US07/787,227
• Time in Patent Office: 2,647 Days
• Field of Search: 623/1, 623/9, 623/12, 428/36.3, 428/36.5, 428/36.91
• US Class Current: 623/1.44
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/34 Macromolecular materials
• CPC Class Codes: C08L 67/02 Polyesters derived from dicarboxylic acids and dihydroxy compounds C08L67/06 takes precedence
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: Y10S 623/926 Synthetic
• CPC Class Codes: Y10T 428/1369 Fiber or fibers wound around each other or into a self-sustaining shape [e.g., yarn, braid, fibers shaped around a core, etc.]
• CPC Class Codes: Y10T 428/1376 Foam or porous material containing
• CPC Class Codes: Y10T 428/1393 Multilayer [continuous layer]

Abstract

A silicone composite vascular graft especially well suited as an arteriovenous (A-V) graft fistula for dialysis application. The graft has the ability to seal around needle puncture holes without externally applied pressure, excellent anti-kink, anti-crush and strength properties, and a smooth non-porous inner surface which reduces thrombus deposition and enhances the graft wall compliance or elasticity.

Claims

1. Composite graft comprising in order:

a. a porous silicone inner layer;

b. a non-porous meld layer;

c. a porous silicone middle layer;

d. a silicone bead;

e. a PET winding; and

,

f. a porous silicone outer layer.

2. A vascular graft comprised of:

a. a fibrous porous wall providing a flexible structure which allows at least some tissue ingrowth and anchoring of the graft in the surrounding tissue;

b. said fibrous porous wall having at least a portion with pores sufficiently small to reduce fibroblast ingrowth into the graft wall;

c. said small-pore portion thereby allowing graft flexibility to be maintained over time; and

,

d. wherein said porous wall comprises a silicone material.

3. A vascular graft comprised of:

a. a fibrous porous wall providing a flexible structure for tissue ingrowth and anchoring of the graft in the surrounding tissue;

b. at least a portion of said fibrous porous wall being comprised of an elastomeric material such as silicone or polyurethane;

c. said elastomeric material providing resilience to resist crushing or kinking of the graft; and

,

d. a spiral bead or rings of polymeric material, said bead or rings providing enhanced kink resistance and crush resistance to the graft.