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Apparatus for the detection of an analyte utilizing mesoscale flow systems

DC
  • US 5,866,345 A
  • Filed: 03/05/1997
  • Issued: 02/02/1999
  • Est. Priority Date: 05/01/1992
  • Status: Expired due to Term
First Claim
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1. A device for detecting the presence of an analyte in a fluid sample, the device comprising:

  • a solid substrate microfabricated to define;

    a sample inlet port;

    a mesoscale flow system comprising;

    a sample flow channel in fluid communication with said inlet port; and

    an analyte detection region in fluid communication with said flow channel comprising a binding moiety immobilized therein for specifically binding said analyte, said detection region having a mesoscale dimension; and

    a detection window disposed in said detection region for transmitting a signal indicating binding of said analyte to said binding moiety to a detection means disposed adjacent to said window.

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