Intraocular implant

• US 5,868,697 A
• Filed: 03/27/1996
• Issued: 02/09/1999
• Est. Priority Date: 05/14/1995
• Status: Expired due to Term

• Current Assignee: Optonol, Ltd. (Alcon Incorporated)
• Original Assignee: Optonol, Ltd. (Alcon Incorporated)
• Inventors: Yaron, Ira, Richter, Jacob, Pinchasik, Gregory
• Primary Examiner(s): JONES, MARYBETH O
• Application Number:
  US08/623,238
• Time in Patent Office: 1,049 Days
• Field of Search: 604/8-10, 604/289, 604/294, 623/4
• US Class Current: 604/8
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

An ophthalmic implant for treatment of glaucoma, a delivery device for implanting such an implant, and a method of implanting such an implant. The implant includes a tube having an inlet end, an outlet end, and a tube passage therebetween, and a disk connected to the tube at the outlet end of the tube. The tube passage has a cross-sectional area sufficiently small to inhibit the flow of aqueous humor through the tube passage. The implant provides a bleb of aqueous humor under the conjunctiva so that the bleb and the elasticity of the conjunctiva assist in regulating the flow of aqueous humor through the tube as a function of the intraocular pressure. The tube at its inlet end has a beveled surface facing away from the iris and one or more circumferential holes. One or more retention projections are provided for anchoring and may be extended outwardly when the implant is implanted in the eyeball. The disk has an outer rim and one or more inner uprights. The implant is implanted by use of a delivery device comprising a handle and a rodlike instrument, with a tip for insertion into the tube passage of the implant and a retention mechanism for retaining the implant. During implantation, the implant is inserted through a slit in a portion of the conjunctiva which normally lies at a distance away from the intended implantation site.

Claims

1. An intraocular implant for implantation in an eyeball comprising:

a tube for implanting into the eyeball, in close proximity to the limbal area of the eyeball, comprising an inlet end, an outlet end, and a tube passage extending between the inlet end and the outlet end for permitting aqueous humor to flow out of the eyeball; and

a disk connected to the tube at the outlet end of the tube for placing on a surface of the eyeball;

wherein the tube has a beveled surface at the inlet end and the beveled surface lies in a first plane forming an angle with a longitudinal axis of the tube and intersecting the longitudinal axis at a first point and the disk lies in a second plane forming an angle with the longitudinal axis and intersecting the longitudinal axis at a second point, wherein a line perpendicular to the longitudinal axis which intersects a line at the intersection of the first and second planes intersects the longitudinal axis between the first point and the second point.

2. An intraocular implant for implantation in an eyeball comprising:

a tube for implanting into the eyeball comprising an inlet end, an outlet end, and a tube passage extending between the inlet end and the outlet end for permitting aqueous humor to flow out of the eyeball; and

a disk connected to the tube at the outlet end of the tube for placing on a surface of the eyeball;

wherein the tube has at least one circumferential hole which opens into the tube passage proximate the inlet end of the tube.

3. An intraocular implant for implantation in an eyeball comprising:

a tube for implanting into the eyeball comprising an inlet end, an outlet end, and a tube passage extending between the inlet end and the outlet end for permitting aqueous humor to flow out of the eyeball; and

a disk connected to the tube at the outlet end of the tube for placing on a surface of the eyeball;

wherein the disk comprises a base, an outer rim, and at least one inner upright, and wherein the base and outer rim form a reservoir having a larger cross-sectional area than the tube passage.

4. An intraocular implant according to claim 3 wherein said at least one inner upright is curved to form an inner rim proximate an axial outlet opening of the tube and substantially bounding the axial outlet opening of the tube, the disk further comprising at least one passageway in the inner rim for enabling flow of aqueous humor from the axial outlet opening through the passageway.

5. An intraocular implant according to claim 3 wherein the disk has an elliptical shape.

6. An intraocular implant for implantation in an eyeball comprising:

a tube for implanting into the eyeball comprising an inlet end, an outlet end, and a tube passage extending between the inlet end and the outlet end for permitting aqueous humor to flow out of the eyeball; and

a disk connected to the tube at the outlet end of the tube for placing on a surface of the eyeball;

wherein the implant has at least one retention projection for anchoring the implant in the eyeball, said retention projection being in a retracted position prior to implantation and then extended outwardly when the implant is implanted in the eyeball.

7. An intraocular implant according to claim 6 wherein said at least one retention projection is extended outwardly by an expansion tool when the implant is implanted in the eyeball.

8. An intraocular implant according to claim 6 wherein said at least one retention projection is constructed of a shape memory material and is extended outwardly when subjected to the heat of the eyeball when the implant is implanted in the eyeball.

9. An intraocular implant for implantation in an eyeball comprising:

a tube for implanting into the eyeball comprising an inlet end, an outlet end, and a tube passage extending between the inlet end and the outlet end for permitting aqueous humor to flow out of the eyeball; and

a disk connected to the tube at the outlet end of the tube for placing on a surface of the eyeball;

wherein the implant comprises at least two uprights proximate an axial outlet opening of the tube and at least one passageway extending between the two uprights and located proximate the axial outlet opening of the tube, wherein the uprights raise the conjunctiva from the axial outlet opening of the tube and the passageway enables flow of aqueous humor away from the axial outlet opening of the tube.

10. An intraocular implant according to claim 9 wherein the passageway extends in a direction generally transverse to a longitudinal axis of the tube.