Injection dart system

• US 5,868,699 A
• Filed: 06/07/1995
• Issued: 02/09/1999
• Est. Priority Date: 06/07/1995
• Status: Expired due to Fees

• Current Assignee: American Colloid Company (Minerals Technologies Incorporated)
• Original Assignee: American Colloid Company (Minerals Technologies Incorporated)
• Inventors: Peterson, David Alan, Eager, Kendra Beth, Woodruff, Keith F.
• Primary Examiner(s): Coggins, Wynn Wood
• Assistant Examiner(s): Sadula, Jennifer R.
• Application Number:
  US08/473,346
• Time in Patent Office: 1,343 Days
• Field of Search: 604/19, 604/49, 604/51, 604/56-57, 604/59-60, 604/93, 604/115-7, 604/130-1, 604/174-5, 604/177-8, 604/194, 604/231-2, 604/239, 604/264, 604/272-4, 604/282 , 604/890.1, 604/891.1, 273/418-20, 273/422-3
• US Class Current: 604/506
• CPC Class Codes: A61D 7/00 Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals for reproduction or fertilisation A61D19/00 ; devices for implanting pellets, radon seeds or the like A61M37/0069
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027

Abstract

An implant dart has a head of solid material and a tubular body that contains one or more drug-delivery implant packages. The head has a blade at its front end with a chisel type point with a beveled end and a scooped face extending rearwardly to the body. The body is formed as a helical coil that makes the body tubular and permits the coil turns to be compressed and engage to make the body relatively rigid when the dart is injected into the subject. A passage from the head to the interior of the body provides fluid communication between the subject'"'"'s body fluids and the implant packages. Wings extend from the head to guide entry of the dart into the subject and to lock it against withdrawal. The complete system comprises at least one dart and an injection mechanism which retains a subject'"'"'s body part on a platen and feeds darts into the body part and generally parallel to the platen.

Claims

1. An implant dart for insertion into an animal body, said implant dart comprising:

a forward head having a first means for penetrating into body tissue so as to permit the entire dart to enter and lodge totally within the body and a second means for non-removably implanting said entair dart within said body,

a tubular body oriented behind said head, said tubular body having a compartment for holding at least one drug-delivery implant container;

said compartment in said tubular body being in fluid communication with said head by a passage defined between said head and said tubular body to permit entry of fluids within the animal body into said compartment;

said forward head and said tubular body being formed from material biologically compatible with said animal body.

2. An implant dart as in claim 1 wherein said head comprises a front end thereof and said tubular body comprises a rear end thereof, said front end being constructed to be sufficiently sharp to pierce body tissue.

3. An implant dart as in claim 2 wherein said head has an outer surface, is of curved shape and includes a face with a scooped shape.

4. An implant dart as in claim 3 wherein the front end of said head is an elongated blade having a forward end, said forward end defining an upper cutting edge and an inwardly and downwardly oriented bevel defined below said cutting edge.

5. An implant dart as in claim 4, wherein said head has a concave radius defined between a rear end portion of said head and a rear end portion of said blade.

6. An implant dart as in claim 2 wherein said tubular body is flexible.

7. An implant dart as in claim 6 wherein the tubular body is formed of at least one turn of a coil of material.

8. An implant dart as in claim 7, wherein said at least one turn is of a helical shape.

9. An implant dart as in claim 6 further comprising an opening at the end of the tubular body remote from the head to permit insertion of an implant into said tubular body.

10. An implant dart as in claim 1 further comprising a plug for sealing the rear end of said tubular body remote from said head.

11. An implant dart for insertion into an animal body, said implant dart comprising:

a head having means for penetrating into body tissue so as to permit the entire dart to enter the body;

a tubular body having a compartment for holding at least one drug-delivery implant container;

said tubular body being pervious to fluids within the animal body so as to permit entry of said fluids within the animal body into said compartment;

said head comprising a front end of said dart and said tubular body comprising a rear end of said dart, said front end of said head being constructed to be sufficiently sharp to pierce body tissue;

said tubular body being flexible;

said tubular body being formed of at least one turn of a coil of material, said at least one turn being of a helical shape; and

the coil having a plurality of turns and stops between the turns of the coil that engage to limit compressive force along the length of the tubular body.

12. An implant dart for insertion into an animal body, said implant dart comprising:

a forward head having means for penetrating into body tissue so as to permit the entire dart to enter the body;

a tubular body oriented behind said head, said tubular body having a compartment for holding at least one drug-delivery container;

said compartment in said tubular body being in fluid communication with said head by a passage defined between said head and said tubular body to permit entry of fluids within the animal body into said compartment; and

at least one stabilizing wing extending from said head back towards said tubular body.

13. An implant dart as in claim 12 wherein said at least one wing overlies at least a part of said tubular body.

14. An implant dart as in claim 12 wherein there are a pair of substantially coplanar stabilizing wings on opposing sides of said head.

15. An implant dart as in claim 14 wherein said wings are located on a plane which passes through the longitudinal axis of the tubular body.

16. An implant dart as in claim 14 wherein said stabilizing wings are formed in a delta shape.

17. An implant dart as in claim 14 wherein each said wing has a slot starting at a rear edge thereof and being generally parallel to the longitudinal axis of the tubular body to permit flexing of a wing inwardly toward the tubular body.

18. An implant dart for insertion into an animal body, said implant dart being formed from material biologically compatible with said animal body and adapted to be non-removably implanted in said animal body, said implant dart comprising at least two separate components including:

a head portion comprising a forward end of said dart, said head portion having a first means for penetrating the animal body to permit said entire dart to enter and lodge totally within the animal body and a second means for non-removably implanting said entair dart within said body,

a tubular body being oriented behind said forward head portion and comprising a rear end of said dart, said tubular body being adapted for holding at least one drug-delivery implant container therein;

said forward head portion defining at least one opening therein in fluid communication with said tubular body for releasing substances in said drug-delivery implant container from said dart;

said forward head and said tubular body being formed from material biologically compatible with said animal body.

19. An implant dart for insertion into a subject comprising:

a head having a front and rear end and an elongated blade at its front end;

a flexible tubular body at the rear end of said head formed of a coil of material;

at least one implant within said tubular body; and

said head having a passage therethrough communicating with the interior of said tubular body.

20. An implant dart for insertion into an animal body, said implant dart comprising:

a head comprising a front end of said dart and having a first means for penetrating into body tissue so as to permit the entire dart to enter and lodge totally within the body and a second means for non-removably implanting said entair dart within said body,

a flexible tubular body comprising a rear end of said dart and having a compartment for holding at least one drug-delivery implant container;

a passage through said head to the interior of said tubular body for providing access into said compartment by fluids within the animal body;

an opening at the end of the tubular body remote from the head to permit insertion of an implant into said tubular body;

said forward head and said tubular body being formed from material biologically compatible with said animal body.

21. A method for implanting a sustained release composition into an animal body, said method being performed with an implant dart including a head having means for penetrating into body tissue so as to permit the entire dart to enter the body, a tubular body having a compartment for holding a drug-delivery implant container, a passage between said head and said compartment to permit entry of fluids within the animal body into said compartment, said method comprising the steps of:

introducing into said compartment a drug-delivery implant containing said sustained release composition; and

inserting said implant dart into the interior of a part of the animal body so that the dart is entirely within the body part and said fluids within the animal body are in fluid communication with said drug-delivery implant in said compartment.

22. The method of claim 21 wherein the body part into which said implant dart is inserted is an animal'"'"'s ear and said inserting step comprises:

retaining the ear so that a target portion thereof extends along a path of travel of said dart while an adjacent portion extends laterally of said path, whereby an angular bend in the ear is exposed to said dart; and

advancing said dart towards the ear so that it enters the ear at the angular bend and advances along the target portion.

23. The method of claim 21 wherein the body part into which said implant dart is inserted is an ear containing cartilage, said method being performed with the aid of an applicator including a housing having an elongated bore dimensioned to receive the dart and terminating in an forward opening in said housing, said forward opening being defined by a perimeter of said bore, and engagement means for receiving and retaining the ear, said inserting step comprising:

positioning said engagement means relative to said housing so that a target portion of the ear is positioned generally parallel to and in front of said forward opening with the cartilage thereof outside the perimeter of the bore, while an adjacent area of the ear extends laterally of said forward opening so as to expose a bend in the ear at said forward opening; and

placing a dart in said bore means at a distance rearward of said forward opening and accelerating said dart towards and out of said forward opening.