×

Oral osmotic device with hydrogel driving member

  • US 5,869,096 A
  • Filed: 12/09/1994
  • Issued: 02/09/1999
  • Est. Priority Date: 07/14/1989
  • Status: Expired due to Term
First Claim
Patent Images

1. An osmotic device for treatment of Parkinson'"'"'s disease by the controlled delivery of a drug comprising levodopa to the mucosa of the oral cavity of a patient over an extended delivery period of between 0.5 to 12 hours, the device comprising:

  • a wall defining a compartment and an exit passageway, the wall being formed of a semipermeable material;

    a drug layer comprising a dose of 0.05 ng to 500 mg levodopa and a suspending agent therefore located in the compartment adjacent the exit passageway, the exit passageway communicating the drug layer with the exterior, and a driving layer comprising a hydrophilic polymer located in the compartment adjacent the drug layer and opposite the exit passageway;

    wherein the device has a smooth oval shape with an aspect ratio in the range of about 1.2;

    1 to about 3;

    1, a height of about 0.5 to about 10 mm, and a volume of less than about 2 cm3 and delivers levodopa through the exit passageway to the mucosa within the oral cavity.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×