Method and apparatus to remove data outliers, produced by external disturbance, in internally measured signals in an implantable cardiac stimulator

• US 5,871,509 A
• Filed: 04/02/1998
• Issued: 02/16/1999
• Est. Priority Date: 04/02/1998
• Status: Expired due to Term

• Current Assignee: Pacesetter AB (Abbott Laboratories)
• Original Assignee: Pacesetter AB (Abbott Laboratories)
• Inventors: Noren, Kjell
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US09/053,691
• Time in Patent Office: 320 Days
• Field of Search: 607/2, 607/3, 607/5, 607/9, 607/11, 607/32, 128/901, 128/902
• US Class Current: 607/9
• CPC Class Codes: A61N 1/37 Monitoring; Protecting
• CPC Class Codes: A61N 1/3718 Monitoring of or protection against external electromagnetic fields or currents
• CPC Class Codes: Y10S 128/901 Suppression of noise in electric signal

Abstract

In a method and apparatus for removing data outliers in measured signals in an implanted medical apparatus, such as data outliers produced by GSM disturbance picked up by an implanted cardiac stimulator lead and superimposed on the sensed cardiac activity signal, the signal from the implanted lead is subjected to median filtering. The median filtering minimizes, or eliminates, the effect of highly aberrational data points in the incoming signal, without the necessity of actually removing the components in the signal produced by the disturbance from the incoming signal itself. Since no portion of the actual incoming signal is removed by the median filtering, the data integrity of the sensed cardiac signal is preserved. The signal processed by median filtering, possibly subjected to subsequent post filtering, is then supplied to a detector within the implanted stimulator, which performs the desired detection on the filtered signal, with the result of the detection then being used to control operation of the implanted stimulator.

Claims

1. A method for removing an effect produced by an external disturbance on an internally obtained signal in an implantable cardiac stimulator, comprising the steps of:

intracorporeally acquiring an intracorporeally-produced physiological signal from a subject, said physiological signal representing data susceptible to a corrupting effect by an extracorporeally-produced disturbance resulting in a corrupted signal;

substantially removing said corrupting effect on said data in said corrupted signal while substantially preserving said data in said corrupted signal by median filtering said corrupted signal; and

controlling intracorporeal administration of a medical therapy dependent on said data after median filtering said corrupted signal.

2. A method as claimed in claim 1 wherein the step of controlling intracorporeal administration of a medical therapy comprises:

detecting a selected characteristic from said data after median filtering of said corrupted signal;

producing a control signal dependent on said characteristic; and

adjusting said medical therapy dependent on said characteristic.

3. A method as claimed in claim 1 wherein a step of intracorporeally acquiring an intracorporeally-produced physiological signal comprises intracorporeally acquiring a cardiac activity signal using an implanted electrode lead, said cardiac activity signal being susceptible to a corrupting effect by GSM disturbance.

4. A method as claimed in claim 3 wherein the step of controlling intracorporeal administration of a medical therapy dependent on said data comprises the steps of:

detecting a selected characteristic from said cardiac activity signal after median filtering said cardiac signal corrupted by said GSM disturbance;

generating a pacing control signal dependent on said characteristic; and

using said pacing control signal to control a pulse generator, which emits stimulation pulses, to alter at least one of a stimulation rate and an amplitude of said stimulation pulses.

5. A method as claimed in claim 1 wherein said physiological signal is an analog signal, and comprising the additional step of converting said analog signal into a digital signal, and wherein the step of median filtering said corrupted signal comprises median filtering said corrupted signal in a digitally operating median filter.

6. A method as claimed in claim 1 wherein the step of median filtering said corrupted signal produces a median filtered signal, and comprising the additional step of post filtering said median filtered signal to produce a post filtered signal containing said data, and wherein the step of controlling intracorporeal administration of a medical therapy comprises controlling intracorporeal administration of a medical therapy dependent on the data contained in said post filtered signal.

7. A method as claimed in claim 6 wherein the step of post filtering said median filtered signal comprises bandpass filtering said median filtered signal.

8. A method as claimed in claim 6 comprising the additional steps of comparing said corrupted signal to said post filtered signal to identify a noise level in said corrupted signal, and preventing a post filtered signal, produced from a corrupted signal having a noise level which exceeds a predetermined threshold, from being used for controlling intracorporeal administration of said medical therapy.

9. A method as claimed in claim 1 wherein the step of median filtering said corrupted signal comprises median filtering said corrupted signal in a median filter having a three-point sorting network.

10. A method as claimed in claim 1 wherein the step of median filtering said corrupted signal comprises median filtering said corrupted signal in a median filter having a five-point sorting network.

11. An implantable cardiac stimulator comprising:

pulse generator means for emitting stimulation pulses having an amplitude and a rate;

a sensing amplifier;

an electrode lead, adapted for implantation in a subject, connected to said pulse generator means and to said sensing amplifier for delivering said stimulation pulses to cardiac tissue and for acquiring an electrical signal containing data representing cardiac activity, said electrical signal and the data contained therein being susceptible to a corrupting effect by an extracorporeally-produced disturbance resulting in a corrupted signal, said corrupted signal being supplied to said sense amplifier and said sense amplifier producing an amplifier output signal containing said data;

median filter means, supplied with said amplifier output signal, for substantially removing said corrupting effect on said data while substantially preserving said data by median filtering said amplifier output signal;

means, supplied with said data from said median filter means, for controlling intracorporeal administration of a medical therapy dependent on the data with said corrupting effect substantially removed therefrom after median filtering; and

a housing adapted for implantation in a subject, said housing containing said pulse generator means, said sense amplifier, said median filter means and said means for controlling intracorporeal administration of a medical therapy.

12. A cardiac stimulator as claimed in claim 11 further comprising:

means for detecting a selected characteristic from said data after median filtering of said amplifier output signal;

means for producing a control signal dependent on said characteristic; and

said means for controlling comprising means for adjusting said medical therapy dependent on said characteristic.

13. A cardiac stimulator as claimed in claim 12 wherein said means for adjusting said medical therapy comprises means for controlling said pulse generator means for adjusting at least one of said amplitude and said rate of said stimulation pulses.

14. A cardiac stimulator as claimed in claim 11 wherein said electrical signal acquired by said electrode lead is an analog signal, and said stimulator further comprising an analog-to-digital converter which converts said amplifier output signal into a digital signal, and wherein said median filter means comprises a digitally operating median filter supplied with said digital signal, said analog-to-digital converter being contained in said housing.

15. A cardiac stimulator as claimed in claim 11 wherein said median filter means produces a median filtered signal, and further comprising a post filter supplied with said median filtered signal which produces a post filtered signal containing said data, and wherein said means for controlling intracorporeal administration of a medical therapy comprises means for controlling intracorporeal administration of a medical therapy dependent on data contained in said post filtered signal, said post filter being contained in said housing.

16. A cardiac stimulator as claimed in claim 15 wherein said post filter comprises a bandpass filter.

17. A cardiac stimulator as claimed in claim 15 further comprising means for comparing said amplifier output signal to said post filtered signal for identifying a noise level in said amplifier output signal, and wherein said means for controlling comprises means for precluding use of a post filtered signal produced by an amplifier output signal containing a noise level which exceeds a predetermined threshold.

18. A cardiac stimulator as claimed in claim 11 wherein said median filter means comprises a three-point sorting network.

19. A cardiac stimulator as claimed in claim 11 wherein said median filter means comprises a five-point sorting network.