Composition containing a radioactive component for treatment of vessel wall
First Claim
1. A method for inhibiting restenosis at a vessel wall region comprising the steps:
- providing an adhesive including a radioactive material; and
applying said adhesive to said vessel wall region.
2 Assignments
0 Petitions
Accused Products
Abstract
A method and composition for inhibiting restenosis. The composition includes an adhesive or polymeric material having a radioactive component dispersed therethrough. A biologically compatible adhesive including a radioactive material is applied to a vessel region where inhibition of restenosis is desired in a preferred method. In one composition, the radioactive material is admixed with the adhesive. In another composition, the radioactive material is chemically bonded to a polymeric adhesive. The adhesive is preferably cured in place. The radioactive material has a preferred half life of less than six months. In one method, the application of adhesive is followed by stent placement, leaving radioactive adhesive extending beyond both stent ends. The application can include forcing adhesive from a double walled balloon having a porous outer wall.
128 Citations
18 Claims
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1. A method for inhibiting restenosis at a vessel wall region comprising the steps:
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providing an adhesive including a radioactive material; and applying said adhesive to said vessel wall region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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- 10. A composition for use in inhibiting restenosis in a body comprising an adhesive composition and a radioactive material dispersed therethrough, wherein the adhesive composition is adapted to be absorbed by the body after a period of time.
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15. A composition for use in inhibiting restenosis comprising an adhesive composition and a radioactive material dispersed therethrough, wherein said adhesive composition is a moisture cure adhesive selected from the group consisting of:
- fibrin glue and cyanoacrylates.
- View Dependent Claims (16, 17)
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18. A method for inhibiting cell growth in a tissue region of a human body comprising the steps:
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providing an adhesive including a radioactive material; applying said adhesive to said tissue region; and allowing said adhesive to cure while said adhesive is applied to said tissue region.
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Specification