Three dimensional digital subtraction magnetic resonance angiography with limited k-space mask

• US 5,873,825 A
• Filed: 04/06/1998
• Issued: 02/23/1999
• Est. Priority Date: 04/11/1997
• Status: Expired due to Term

• Current Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Original Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Inventors: Frayne, Richard, Grist, Thomas M, Mistretta, Charles A, Korosec, Frank R
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): MANTIS MERCADER, ELENI M
• Application Number:
  US09/055,501
• Time in Patent Office: 323 Days
• Field of Search: 600/410, 600/419, 600/420, 324/306, 324/307, 324/309, 324/312
• US Class Current: 600/410
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/4822 in three dimensions
• CPC Class Codes: G01R 33/563 of moving material, e.g. flow contrast angiography

Abstract

A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. A difference image is produced by subtracting a mask formed by central region k-space sampling from a selected image frame formed by central region and peripheral regions k-space sampling.

Claims

1. A method for producing a contrast enhanced NMR image with an MRI system that performs a pulse sequence which samples a region of k-space, the steps comprising:

a) acquiring a mask NMR data set by performing the pulse sequence to sample only a central portion of said k-space;

b) acquiring an NMR image data set by performing the pulse sequence to sample said central portion of said k-space and a peripheral portion of said k-space;

c) producing a difference data set by subtracting the mask NMR data set from the image NMR data set; and

d) reconstructing the NMR image from the difference data set.

2. The method as recited in claim 1 in which the mask NMR data set and the NMR image data set are acquired during a dynamic study of a subject after injection of a contrast agent.

3. The method as recited in claim 2 in which the pulse sequence is repeatedly performed during the dynamic study to form a plurality of acquired NMR data sets, the mask NMR data set is selected from one of the acquired NMR data sets, and the NMR image data set is selected from another one of the acquired NMR data sets.

4. The method as recited in claim 1 in which the pulse sequence is performed a plurality of times to acquire the mask NMR data set, and the pulse sequence is performed a plurality of times to acquire the NMR image data set.