Method and apparatus for ventricular fibrillation detection

• US 5,876,349 A
• Filed: 08/08/1997
• Issued: 03/02/1999
• Est. Priority Date: 08/08/1997
• Status: Expired due to Term

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Hewlett-Packard Company (HP Inc.)
• Inventors: Nakagawa, Michael, Wang, Jyh-Yun J.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US08/908,847
• Time in Patent Office: 571 Days
• Field of Search: 607/5, 600/515, 600/517, 600/518
• US Class Current: 600/518
• CPC Class Codes: A61B 5/361 Detecting fibrillation

Abstract

Provided are a method and apparatus for assessing the chaotic nature of a waveform representation of heart function. The method and apparatus accomplish their objects via the following. An indicator of triangular-like components within a waveform representation of heart function is calculated. An indicator of an area encompassed by the waveform representation indicative of heart function is calculated. A ratio is calculated utilizing the calculated indicator of an area and calculated indicator of triangular-like components to assess the chaotic nature of the waveform representation of heart function. Additionally, a ventricular fibrillation index is calculated. The calculated ventricular fibrillation index is utilized, in two dimensional space, with the ratio that is calculated utilizing the calculated indicator of an area and the calculated indicator of triangular-like components to assess the likelihood of ventricular fibrillation based upon waveform representation of heart function. Further additionally, a minimum ventricular fibrillation index is calculated. The calculated minimum ventricular fibrillation index is utilized, in two dimensional space, with the ratio that is calculated utilizing the calculated indicator of an area and the calculated indicator of triangular-like components to assess the likelihood of ventricular fibrillation based upon waveform representation of heart function. The minimum calculated ventricular fibrillation is also utilized in one dimensional space to assess the likelihood of ventricular fibrillation based upon waveform representation of heart function.

Claims

1. A method for assessing the chaotic nature of a waveform representation of heart function, said method comprising the steps of:

calculating an indicator of triangular-like components within said waveform representation;

calculating an indicator of an area encompassed by said waveform representation;

calculating a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components; and

assessing the chaotic nature of said waveform representation of heart function by utilizing said ratio of said calculated indicator of an area and said calculated indicator of triangular-like components.

2. The method of claim 1, wherein said step of calculating an indicator of triangular-like components further comprises the steps of:

sampling said waveform representation of heart function to obtain successively sampled values; and

summing the absolute values of the differences of said successively sampled values of said waveform representation of heart function.

3. The method of claim 1, wherein said step of calculating an indicator of an area further comprises the steps of:

sampling said waveform representation of heart function to obtain successively sampled values; and

summing the absolute values of said successively sample values of said waveform representation of heart function.

4. The method of claim 1, wherein said step of assessing the chaotic nature of said waveform representation of heart function by utilizing said ratio further comprises the steps of:

generating a plurality of time-shifted versions of said waveform representation of heart function; and

utilizing said ratio with said time-shifted versions of said waveforms to obtain a normalized residual such that said obtained normalized residual is indicative of the chaotic nature of said waveform.

5. A method for assessing the likelihood of ventricular fibrillation on the basis of a waveform representation of heart function, said method comprising the steps of:

calculating an indicator of triangular-like components within a waveform representation;

calculating an indicator of an area encompassed by said waveform representation;

calculating a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components;

calculating a ventricular fibrillation index; and

assessing the chaotic nature of said waveform representation of heart function by utilizing in at least a two-dimensional decision space said calculated ventricular fibrillation index with said ratio of said calculated indicator of an area and said calculated indicator of triangular-like components.

6. The method of claim 5, wherein said step of calculating a ventricular fibrillation index further comprises the steps of:

sampling said waveform representation of heart function to obtain successively sampled values;

summing the absolute values of at least one sum drawn upon a sampled value of said waveform and a previously sampled value of said waveform;

summing the values of at least one sum drawn upon the absolute value of said sampled value and the absolute value of said previously sampled value of said waveform; and

calculating said ventricular fibrillation index based upon said summed absolute values of said at least one sum and said summed values of at least one sum drawn upon the absolute value of said sampled value and the absolute value of said previously sampled value.

7. The method of claim 5, wherein said step of calculating a ventricular fibrillation index further comprises the steps of:

generating a plurality of time-shifted versions of said waveform representation of heart function;

calculating a plurality of ventricular fibrillation indices based upon said plurality of time-shifted versions of said waveform representation of heart function; and

selecting said calculated ventricular fibrillation index to be the minimum ventricular fibrillation index extant within said calculated plurality of ventricular fibrillation indices.

8. The method of claim 7, wherein said step of calculating a plurality of ventricular fibrillation indices further comprises the steps of:

calculating each of said plurality of ventricular fibrillation indices by doing the following for each of said plurality of time-shifted versions;

sampling each of said plurality of time-shifted versions to obtain successively sampled values;

summing the absolute values of at least one sum drawn upon a sampled value of each of said plurality of time-shifted versions and a previously sampled value of each of said plurality of time-shifted versions;

summing the values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions; and

calculating said ventricular fibrillation index based upon said summed absolute values of said at least one sum and said summed values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions.

9. The method of claim 5, wherein said step of calculating an indicator of triangular-like components further comprises the steps of:

sampling said waveform representation of heart function to obtain successively sampled values; and

summing the absolute values of the differences of successively sampled values of said waveform representation of heart function.

10. The method of claim 5, wherein said step of calculating an indicator of an area further comprises the steps of:

sampling said waveform representation of heart function to obtain successively sampled values; and

summing the absolute values of successive sample values of said waveform representation of heart function.

11. The method of claim 5, wherein said step of utilizing, in at least a two-dimensional decision space, said calculated ventricular fibrillation index with a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components further comprises the step of utilizing said calculated ventricular fibrillation index with a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components in comparison with a two-dimensional comparison threshold to assess the likelihood of ventricular fibrillation.

12. A method for assessing the likelihood of ventricular fibrillation on the basis of a waveform representation of heart function, said method comprising the steps of:

calculating a minimum ventricular fibrillation index; and

assessing the likelihood of ventricular fibrillation based upon a waveform representation of heart function by utilizing in at least a one-dimensional decision space said calculated minimum ventricular fibrillation index.

13. The method of claim 12, wherein said step of calculating a minimum ventricular fibrillation index further comprises the steps of:

calculating an estimated period for said waveform representation of heart function;

generating a plurality of time-shifted versions of said waveform representation of heart function shifted relative to said calculated estimated period;

calculating a plurality of ventricular fibrillation indices based upon said plurality of versions of said waveform representation of heart function shifted relative to said calculated estimated period; and

selecting said calculated minimum ventricular fibrillation index to be the minimum ventricular fibrillation index extant within said calculated plurality of ventricular fibrillation indices.

14. The method of claim 13, wherein said step of calculating a plurality of ventricular fibrillation indices further comprises the steps of:

calculating each of said plurality of ventricular fibrillation indices by doing the following for each of said plurality of time-shifted versions;

sampling each of said plurality of time-shifted versions to obtain successively sampled values;

summing the absolute values of at least one sum drawn upon a sampled value of each of said plurality of time-shifted versions and a previously sampled value of each of said plurality of time-shifted versions;

summing the values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions; and

calculating said ventricular fibrillation index based upon said summed absolute values of said at least one sum and said summed values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions.

15. The method of claim 13, wherein said step of calculating an estimated period further comprises the steps of:

sampling said waveform representation of heart function to obtain successively sampled values;

summing the absolute values of successive samples of said waveform;

summing the absolute value of the differences between successive samples of said waveform; and

calculating said estimated period to be a ratio of said summed absolute values of successive samples to said summed absolute value of the differences between successive samples of said waveform.

16. An apparatus for assessing the chaotic nature of a waveform representation of heart function, said apparatus comprising:

means for calculating an indicator of triangular-like components within said waveform representation;

means for calculating an indicator of an area encompassed by said waveform representation;

means for calculating a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components; and

means for assessing the chaotic nature of said waveform representation of heart function by utilizing said ratio of said calculated indicator of an area and said calculated indicator of triangular-like components.

17. The apparatus of claim 16, wherein said means for calculating an indicator of triangular-like components further comprises:

means for sampling said waveform representation of heart function to obtain successively sampled values;

means for summing absolute values of the differences of successively sampled values of said waveform representation of heart function.

18. The apparatus of claim 16, wherein said means for calculating an indicator of an area further comprises:

means for sampling said waveform representation of heart function to obtain successively sampled values; and

means for summing absolute values of successive sample values of said waveform representation of heart function.

19. The apparatus of claim 16, wherein said means for utilizing said ratio further comprises:

means for generating a plurality of time-shifted versions of said waveform representation of heart function; and

means for utilizing said ratio with said time-shifted versions of said waveforms to obtain a normalized residual such that said obtained normalized residual is indicative of the chaotic nature of said waveform.

20. An apparatus for assessing the likelihood of ventricular fibrillation on the basis of a waveform representation of heart function, said apparatus comprising:

means for calculating an indicator of triangular-like components within a waveform representation;

means for calculating an indicator of an area encompassed by said waveform representation;

means for calculating a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components;

means for calculating a ventricular fibrillation index; and

means for assessing the likelihood of ventricular fibrillation based upon said waveform representation of heart function by utilizing in at least a two-dimensional decision space said calculated ventricular fibrillation index with a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components.

21. The apparatus of claim 20, wherein said means for calculating a ventricular fibrillation index further comprises:

means for sampling said waveform representation of heart function to obtain successively sampled values;

means for summing absolute values of at least one sum drawn upon a sampled value of said waveform and a previously sampled value of said waveform;

means for summing values of at least one sum drawn upon the absolute value of said sampled value and the absolute value of said previously sampled value of said waveform; and

means for calculating said ventricular fibrillation index based upon said summed absolute values of said at least one sum and said summed values of at least one sum drawn upon the absolute value of said sampled value and the absolute value of said previously sampled value.

22. The apparatus of claim 20, wherein said means for calculating a ventricular fibrillation index further comprises:

means for generating a plurality of time-shifted versions of said waveform representation of heart function;

means for calculating a plurality of ventricular fibrillation indices based upon said plurality of time-shifted versions of said waveform representation of heart function; and

means for selecting said calculated ventricular fibrillation index to be the minimum ventricular fibrillation index extant within said calculated plurality of ventricular fibrillation indices.

23. The apparatus of claim 22, wherein said means for calculating a plurality of ventricular fibrillation indices further comprises:

means for calculating each of said plurality of ventricular fibrillation indices wherein said means for calculating is capable of doing the following functions for each of said plurality of time-shifted versions;

sampling each of said plurality of time-shifted versions to obtain successively sampled values;

summing absolute values of at least one sum drawn upon a sampled value of each of said plurality of time-shifted versions and a previously sampled value of each of said plurality of time-shifted versions;

summing values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions; and

calculating said ventricular fibrillation index based upon said summed absolute values of said at least one sum and said summed values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions.

24. The apparatus of claim 20, wherein said means for calculating an indicator of triangular-like components further comprises:

means for sampling said waveform representation of heart function to obtain successively sampled values; and

means for summing the absolute values of the differences of successively sampled values of said waveform representation of heart function.

25. The apparatus of claim 20, wherein said means for calculating an indicator of an area further comprises:

means for sampling said waveform representation of heart function to obtain successively sampled values; and

means for summing the absolute values of successive sample values of said waveform representation of heart function.

26. The apparatus of claim 20, wherein said means for utilizing, in at least a two-dimensional decision space, said calculated ventricular fibrillation index with a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components further comprises means for utilizing said calculated ventricular fibrillation index with a ratio of said calculated indicator of an area and said calculated indicator of triangular-like components in comparison with a two-dimensional comparison threshold to assess the likelihood of ventricular fibrillation.

27. An apparatus for assessing the likelihood of ventricular fibrillation on the basis of a waveform representation of heart function, said apparatus comprising:

means for calculating a minimum ventricular fibrillation index; and

means for assessing the likelihood of ventricular fibrillation based upon a waveform representation of heart function by utilizing in at least a one-dimensional decision space said calculated minimum ventricular fibrillation index.

28. The apparatus of claim 27, wherein said means for calculating a minimum ventricular fibrillation index further comprises:

means for calculating an estimated period for said waveform representation of heart function;

means for generating a plurality of time-shifted versions of said waveform representation of heart function shifted relative to said calculated estimated period;

means for calculating a plurality of ventricular fibrillation indices based upon said plurality of versions of said waveform representation of heart function shifted relative to said calculated estimated period; and

means for selecting said calculated minimum ventricular fibrillation index to be the minimum ventricular fibrillation index extant within said calculated plurality of ventricular fibrillation indices.

29. The apparatus of claim 28, wherein said means for calculating a plurality of ventricular fibrillation indices further comprises:

means for calculating each of said plurality of ventricular fibrillation indices wherein said means for calculating is capable of doing the following functions for each of said plurality of time-shifted versions;

sampling each of said plurality of time-shifted versions to obtain successively sampled values;

summing absolute values of at least one sum drawn upon a sampled value of each of said plurality of time-shifted versions and a previously sampled value of each of said plurality of time-shifted versions;

summing values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions; and

calculating said ventricular fibrillation index based upon said summed absolute values of said at least one sum and said summed values of at least one sum drawn upon the absolute value of said sampled value of each of said plurality of time-shifted versions and the absolute value of said previously sampled value of each of said plurality of time-shifted versions.

30. The apparatus of claim 28, wherein said means for calculating an estimated period further comprises:

means for sampling said waveform representation of heart function to obtain successively sampled values;

means for summing absolute values of successive samples of said waveform;

means for summing an absolute value of the differences between successive samples of said waveform; and

means for calculating said estimated period to be a ratio of said summed absolute values of successive samples to said summed absolute value of the differences between successive samples of said waveform.