Stent and method of varying amounts of heparin coated thereon to control treatment
First Claim
1. A stent for placement in a lumen of the body, and said stent placed into said lumen so as to contact said lumen, said stent coated with heparin wherein the stent is coated with enough heparin to insure above 0.7 pmol/cm2 antithrombin III is absorbed by the body when the lumen contacts said stent.
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Accused Products
Abstract
The present invention addresses two previously unresolved problems simultaneously. First, the question concerning the amount of heparin applied to a stent is resolved. That is, the invention set forth herein will demonstrate that by varying the amount of heparin, the practitioner can actually more adequately determine whether in fact the patient will receive the correct dosage to address the problem, and at the right time in which to address the problem. Second, the problem of applying the heparin coating to a stent is addressed. There, specifically, the invention turns to the fashion in which to apply multiple layers of heparin coating to the stent, and to thereby variably adjust the dosage applied to the patient at the lesion site. The present invention does so by providing a method and device for coating a stent with multiple layers of heparin coating. By so doing, the heparin coating is absorbed by the body in a degree which varies with the amount of heparin applied. Thus, contrary to formerly popular belief, the present method allows for the significant adjustment of heparin therapy. And, the stent so coated allows for the variable application of such heparin therapy at the lesion site.
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Citations
8 Claims
- 1. A stent for placement in a lumen of the body, and said stent placed into said lumen so as to contact said lumen, said stent coated with heparin wherein the stent is coated with enough heparin to insure above 0.7 pmol/cm2 antithrombin III is absorbed by the body when the lumen contacts said stent.
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5. A method of placing a stent coated with heparin wherein the amount of heparin is variably adjusted depending on the desired use of the said stent comprising the steps of:
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determining the lesion site to which the stent is to be employed; predetermining the amount of heparin needed on a said stent at said lesion site; coating said stent with the predetermined amount of said heparin wherein the stent is coated with enough heparin to insure at least 0.7 pmol/cm2 uptake of antithrombin III is absorbed by the body at said lesion site. - View Dependent Claims (6, 7, 8)
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Specification