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Electropipettor and compensation means for electrophoretic bias

  • US 5,880,071 A
  • Filed: 12/06/1996
  • Issued: 03/09/1999
  • Est. Priority Date: 06/28/1996
  • Status: Expired due to Term
First Claim
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1. A method of introducing materials from a plurality of sources into a microfluidic system, said microfluidic system having a capillary channel having an end, a voltage source for applying a voltage potential to an electrode in said microfluidic system, said method comprisingcontacting said capillary channel end to a subject material source;

  • applying a voltage to said subject material source with respect to said electrode such that subject material from said source is electrokinetically introduced into said capillary channel toward said microfluidic system;

    selecting a source of spacer material, said spacer material having a selected ionic concentration;

    contacting said capillary channel end into said source of spacer material;

    applying a voltage to said spacer material source with respect to said electrode such that said spacer material is electrokinetically introduced into said capillary channel next to said subject material; and

    repeating the steps above with different material sources so that a plurality of different materials separated by spacer material is electrokinetically introduced into said capillary channel and transported toward said microfluidic system without intermixing said different materials.

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