Microdispensing ophthalmic pump

• US 5,881,956 A
• Filed: 08/08/1996
• Issued: 03/16/1999
• Est. Priority Date: 08/08/1996
• Status: Expired

• Current Assignee: Ben Z. Cohen
• Original Assignee: Ben Z. Cohen
• Inventors: Kelly, Nigel B., Cohen, Ben Z.
• Primary Examiner(s): Kashnikow, Andres
• Assistant Examiner(s): Douglas, Lisa Ann
• Application Number:
  US08/694,206
• Time in Patent Office: 950 Days
• Field of Search: 239/331, 239/333, 239/590, 239/590.5, 222/321.1, 222/321.7, 222/321.9, 222/322, 222/383.1, 222/385, 222/341, 604/289, 604/290, 604/296, 606/107
• US Class Current: 239/333
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: B05B 11/0044 compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means venting means for deformable containers B05B11/047
• CPC Class Codes: B05B 11/0062 Outlet valves actuated by the pressure of the fluid to be sprayed fluid-actuated pump outlet valve arrangements B05B11/1016, B05B11/1022, B05B11/1033, B05B11/1036, B05B11/104, B05B11/1064, B05B11/1097
• CPC Class Codes: B05B 11/1052 Actuation means locking means therefor B05B11/1059; the dispensing stroke being affected by the stored energy of a spring B05B11/109
• CPC Class Codes: B05B 11/1053 combined with means, other than pressure, for automatically opening a valve during actuation; combined with means for automatically removing closures or covers from the discharge nozzle during actuation
• CPC Class Codes: B05B 11/1077 characterised by a particular shape or material B05B11/1076 takes precedence
• CPC Class Codes: B05B 15/30 Dip tubes

Abstract

A microdispensing ophthalmic pump is provided for repeatedly delivering doses as small as 5 microliters within an angular operating range. The pump basically comprises a reservoir, a dispensing cap, an actuator and a pump body with a pump mechanism disposed therein. The pump mechanism is regulated by a limited-travel inlet check valve and a biased-closed outlet check valve. A failsafe mechanism is formed between the actuator and dispensing cap to prevent operation of the pump outside the operating range.

Claims

1. A microdispensing pump for administering minute doses of fluid, said pump comprising:

a pump body formed to define an inner chamber and an inlet chamber with a protrusion extending therein, said inner chamber being in communication with said inlet chamber;

a pump means for urging the fluid through said pump body, said pump means being disposed within said inner chamber; and

an inlet check valve element disposed within said inlet chamber opposite said protrusion, wherein said inlet check valve element regulates the flow of the fluid into the inner chamber and wherein said protrusion limits the movement of said inlet check valve element within said inlet chamber such that a swept volume of said inlet check valve element is less than the volume of the minute dose of fluid.

2. A pump as in claim 1, wherein said inlet chamber has an inner surface formed to substantially define a sphere.

3. A pump as in claim 1, further comprising a dispensing cap extending from said pump means formed to define an outlet chamber with an inlet which communicates with said inner chamber and an outlet check valve element disposed within said outlet chamber which is urged into sealing contact with said inlet of said dispensing cap by a quick return biasing means selected from the group consisting of a resilient rubber ball, a coil spring, and a leaf spring.

4. A microdispensing pump for administering minute doses of fluid, said pump comprising:

a pump body formed to define a hollow inner chamber;

a pump means for drawing fluid into said pump body and urging the fluid therethrough, said pump means being disposed within said inner chamber;

a dispensing cap extending from said pump means formed to define an outlet chamber with an inlet which communicates with said inner chamber, said dispensing cap having an outer surface and a slender discharge nozzle communicating said outer surface with said outlet chamber;

an outlet check valve element disposed within said outlet chamber for controlling flow of the fluid into the outlet chamber; and

a quick return biasing means for urging said outlet check valve element into sealing contact with said inlet of said dispensing cap as the pump means draws the fluid into said pump body.

5. A pump as in claim 4, wherein said quick return biasing means is selected from the group consisting of a resilient rubber ball, a coil spring, and a leaf spring.

6. A microdispensing pump for administering minute doses of fluid, said pump comprising:

a pump body having an inner body being formed to define a hollow inner chamber, an opened upper end and a lower end, with said lower end being formed to define an inlet aperture and inlet valve seat;

a pump mechanism disposed within said pump body having a cylindrical piston slidably and sealingly supported within said inner body, an elongated poppet with a base mounted over the inlet valve seat, a stem extending from said base through said piston in a spatial relationship and a head depending from said stem, said cylindrical piston having an inner surface defining a diameter, said head having a diameter greater than the diameter of said inner surface, and a biasing means for urging said piston into sealing contact with said head of said poppet, wherein the base forms a substantially spherical inlet chamber with the inlet valve seat, at least one port being formed in said base for communicating said inlet chamber with said inner chamber, and a protrusion extending from said base into said inlet chamber;

an inlet check valve element disposed within said inlet chamber for controlling flow of the fluid into the inner chamber whereby said protrusion limits the movement of said inlet check valve element;

a dispensing cap extending from said piston and disposed within said pump body, said dispensing cap formed to define an outlet chamber with an inlet which communicates with said inner chamber when said poppet is not in sealing contact with said piston, and said dispensing cap having an outer surface and a slender discharge nozzle communicating said outer surface with said outlet chamber; and

an outlet check valve element disposed within said outlet chamber for controlling flow of the fluid into the outlet chamber, said outlet check valve element being urged into sealing contact with said inlet of said dispensing cap by a quick return biasing means as the pump administers the minute dose of fluid, whereby force applied to said dispensing cap causes said piston to slide within said cylinder and urge the fluid through said pump mechanism and said nozzle.

7. A pump as in claim 6, further comprising an actuator slidably disposed in said pump body, said actuator having an annular deformable latch mounted thereto with the inner periphery of the latch being unfixed.

8. A pump as in claim 7, further comprising an actuator biasing means for urging the actuator away from said dispensing cap.

9. A pump as in claim 6, further comprising a dip tube for communicating fluid between the reservoir and the inlet aperture of the pump body, said dip tube formed to define a substantially cylindrical passageway which encompasses less volume than the minute dose of fluid.

10. A pump as in claim 9, wherein said pump body further comprises a hook means for securing said dip tube in a predetermined position.

11. A pump as in claim 6, wherein said quick return biasing means is selected from the group consisting of a resilient rubber ball, a coil spring, and a leaf spring.

12. A pump as in claim 6, wherein said pump body includes a substantially cylindric outer shell formed to define a dispensing aperture juxtaposed with said nozzle.

13. A pump as in claim 12, wherein a sight is formed about the dispensing aperture of said pump body.

14. A pump as in claim 6, wherein said outer surface of said dispensing cap is formed to define a conical rim about said discharge nozzle.

15. A pump as in claim 13, wherein said outer surface of said dispensing cap forms an annular depression about said conical rim.

16. A pump as in claim 6, wherein said discharge nozzle has a length to throat ratio of approximately 7 to 1.

17. A pump as in claim 6, wherein said protrusion is formed to define a swept volume of said inlet check valve element less than the volume of the minute dose of fluid.

18. A microdispensing pump with a discharge aperture for administering minute doses of fluid with the discharge aperture being oriented within an angular operating range, said pump comprising:

a dispensing cap formed about an axis having an outer surface formed to define the discharge aperture, said dispensing cap also formed to define an outlet chamber and a discharge nozzle communicating said outlet chamber with the discharge aperture, and said outer surface also being formed to define a slot;

a pump means for delivering fluid to said dispensing cap, said pump means communicating with said outlet chamber;

an actuator disposed about said axis having an inner actuating surface facing said dispensing cap with an actuating member extending therefrom, said actuating member being aligned with at least a portion of said slot, said actuator capable of translation along said axis; and

a failsafe ball disposed within said slot, wherein said ball is aligned with said actuating member where the discharge aperture is oriented within the operating range.

19. A pump as in claim 18, wherein said slot is formed with a first surface defining an acute angle of 25°

relative to said axis and a second surface defining an obtuse angle of 110°

relative to said axis.

20. A pump as in claim 18, further comprising an annular deformable latch mounted to said actuator with an unfixed inner periphery.

21. A pump as in claim 18, further comprising an actuator biasing means for urging said actuator from said dispensing cap.

22. A pump as in claim 18, further comprising a dip tube for communicating the fluid to the pump means formed to define a substantially cylindrical passageway encompassing less volume than the minute dose of fluid.

23. A pump as in claim 18, further comprising at least one check valve means for controlling the flow of the fluid through said pump means.

24. A microdispensing pump for administering minute doses of fluid within an angular operating range, said pump comprising:

a reservoir having a closed bottom for accommodating the fluid and an opened top defining a neck;

a pump body having a substantially cylindrical outer shell with an opened upper portion formed to define a dispensing aperture and a lower portion disposed about said neck, a substantially cylindric inner body disposed co-axially within said outer shell and a transverse annular bulkhead joining said outer shell and said inner body, said inner body being formed to define a hollow cylindrical inner chamber, an opened upper end and a lower end, with said lower end being formed to define an inlet aperture and inlet valve seat;

a pump mechanism disposed within said pump body having a cylindrical piston slidably and sealingly supported within said inner body, an elongated poppet with a base mounted over the inlet valve seat, a stem extending from said base through said piston in a spatial relationship and a head depending from said stem, said cylindrical piston having an inner surface defining a diameter, said head having a diameter greater than the diameter of said inner surface, and a biasing means provided to urge said piston into sealing contact with said head of said poppet, wherein the base forms a substantially spherical inlet chamber with the inlet valve seat, at least one port being formed in said base for communicating said inlet chamber with said inner chamber, and a protrusion extending from said base into said inlet chamber;

an inlet check valve element disposed within said inlet chamber for controlling flow of the fluid into the inner chamber whereby said protrusion limits the movement of said inlet check valve element;

an actuator slidably disposed in the upper portion of the outer shell, said actuator having an inner actuating surface facing said inner body with an actuating member extending therefrom;

a dispensing cap extending from said piston and disposed within said upper portion of said pump body between said actuator and said inner body, said dispensing cap formed to define an outlet chamber with an inlet which communicates with said inner chamber when said poppet is not in sealing contact with said piston, said dispensing cap having an outer surface and a slender discharge nozzle communicating said outer surface with said outlet chamber, said nozzle being juxtaposed with said dispensing aperture of said pump body, and said dispensing cap having an upper surface facing said inner actuating surface formed to define a slot, a portion of said slot being aligned with said actuating member;

a failsafe ball disposed within said slot, wherein said ball being aligned with said actuating member where the pump is oriented within the operating range; and

an outlet check valve element disposed within said outlet chamber for limiting flow of the fluid into the outlet chamber, said outlet check valve element being urged into sealing contact with said inlet of said dispensing cap by a quick return biasing means as the pump administers the minute dose of fluid, whereby force applied to said actuator is transferred to said dispensing cap through said actuating member and said failsafe ball with the pump being oriented within the operating range and whereby said dispensing cap causing said piston to slide within said cylinder and urge the fluid through said pump mechanism and said nozzle.

25. A pump as in claim 24, wherein said slot is formed with a first surface defining an acute angle of 25°

relative to said axis of said pump body and a second surface defining an obtuse angle of 110°

relative to said axis of said pump body.

26. A pump as in claim 24, further comprising a dip tube for communicating the fluid between said reservoir and said inlet aperture of said inner body, said dip tube formed to define a substantially cylindrical passageway which encompasses less volume than the minute dose of fluid.

27. A pump as in claim 26, wherein said pump body further comprises a hook means for securing said dip tube in a predetermined portion.

28. A pump as in claim 24, wherein an annular deformable latch with an unfixed inner periphery is mounted to said actuator and disposed between said dispensing cap and said bulkhead.

29. A pump as in claim 24, further comprising an actuator biasing means for urging said actuator from said dispensing cap.

30. A pump as in claim 24, wherein said quick return biasing means is selected from the group consisting of a resilient rubber ball, a coil spring and a leaf spring.

31. A pump as in claim 24, wherein said outer surface of said dispensing cap is formed to define a conical rim about said discharge nozzle.

32. A pump as in claim 31, wherein said outer surface of said dispensing cap forms an annular depression about said conical rim.

33. A pump as in claim 24, wherein said discharge nozzle has a length to throat ratio of 7 to 1.

34. A pump as in claim 24, wherein said protrusion is formed to define a swept volume of said inlet check valve element less than the volume of the minute dose of fluid.

35. A microdispensing pump for repeatedly administering a predetermined minute dose of fluid, said pump comprising:

a pump body formed with a hollow inner chamber;

pump means for urging the predetermined dose of fluid through said pump body;

an actuator mounted on said pump means for actuating said pump means; and

resistance means for creating a predetermined amount of resistance to the actuating of said pump means by said actuator, wherein said resistance means includes a deformable latch, whereby a force sufficient to administer the predetermined dose of fluid is required to overcome the predetermined amount of resistance.