Drug infusion catheter and method
First Claim
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1. A fluid infusion catheter for use in a blood vessel defined by a wall, comprising:
- an elongated tubular body having a proximal and a distal end and an outer surface and defining a passage therein;
at least one flexible bristle fixedly mounted adjacent said outer surface of said body;
said bristle having a proximal and a distal end and a passage therethrough in flow communication with said passage in said body so that a fluid can be directed through said body and said bristle and to the vessel wall without occlusion of the vessel.
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Abstract
A method and apparatus of delivery of a drug (or substance) is disclosed which involves (1) injecting a drug into the tissue of the blood vessel; (2) maintaining the delivery system as symmetrical as possible in tortuous blood vessels, and (3) providing a preferably constant flow of blood during the drug treatment.
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Citations
29 Claims
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1. A fluid infusion catheter for use in a blood vessel defined by a wall, comprising:
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an elongated tubular body having a proximal and a distal end and an outer surface and defining a passage therein; at least one flexible bristle fixedly mounted adjacent said outer surface of said body;
said bristle having a proximal and a distal end and a passage therethrough in flow communication with said passage in said body so that a fluid can be directed through said body and said bristle and to the vessel wall without occlusion of the vessel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of treating a vessel defined by a wall with a fluid without occlusion thereof, comprising:
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mounting at least one flexible bristle adjacent the outer surface of an elongated body of a catheter; inserting into a vessel said catheter having said elongated body with a passage in flow communication with said bristle with a passage therethrough; retaining said bristle in a flexed state adjacent said outer surface of said elongated body during said inserting; allowing said bristle to flex toward the vessel wall at a predetermined location; pumping fluid through said passages in said body and bristle and against the vessel wall while blood flows around said body and bristle. - View Dependent Claims (21, 22)
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23. A method of treating a vessel with a radiation source, comprising:
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providing a source on a catheter body having an outer surface; providing a plurality of bristles having a proximal and a distal end, said bristles being fixedly mounted adjacent said outer surface of said body; providing a movable sheath over said body which shields said source and holds said bristles in a retracted position; advancing said body with said source while said source is covered by said sheath to a predetermined location in a vessel; exposing said bristles and said source by retraction of said sheath; allowing said bristles to extend toward the vessel wall; centralizing said source in the vessel with said bristles. - View Dependent Claims (24, 25, 26)
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27. A fluid infusion catheter for use in a blood vessel defined by a wall, comprising:
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an elongated tubular body having a proximal and a distal end and an outer surface and defining a passage therein; at least one flexible bristle having a passage therethrough in flow communication with said passage in said body so that a fluid can be directed through said body and said bristle and to the vessel wall without occlusion of the vessel; said bristle is selectively retained adjacent said outer surface of said body.
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28. A method of treating a vessel defined by a wall with a fluid without occlusion thereof, comprising:
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inserting into a vessel a catheter having an elongated body with a passage in flow communication with at least one flexible bristle with a passage therethrough; retaining said bristle in a retracted state with a movable sheath during said inserting; allowing said bristle to flex toward the vessel wall at a predetermined location; pumping a fluid through said passages in said body and bristle and against the vessel wall while blood flows around said body and bristle; using a plurality of bristles which, upon retraction of said sheath from said body, flex to extend radially in contact with said wall to centralize said body in the vessel.
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29. A method of treating a vessel defined by a wall with a fluid without occlusion thereof, comprising:
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inserting into a vessel a catheter having an elongated body; using concentric tubes to create an annular passage in said body with said annular passage in flow communication with a plurality of bristles with a passage therethrough; advancing said concentric tubes over a guidewire; using said bristles to close off an end of said annular passage; providing a taper on said bristles; using a plurality of rows of bristles extending from said body; retaining said bristles in a retracted state with a movable sheath during said inserting; allowing said bristles to flex toward the vessel wall at a predetermined location upon retraction of said sheath; allowing said bristles to contact the vessel upon retraction of said sheath, pumping fluid through said annular passage in said body and said bristles and against the vessel wall while blood flows around said body and bristles.
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Specification