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Compositions and methods for preventing and treating allograft rejection

  • US 5,883,082 A
  • Filed: 11/23/1994
  • Issued: 03/16/1999
  • Est. Priority Date: 08/14/1990
  • Status: Expired due to Term
First Claim
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1. A composition for treating allograft rejection comprising an oligonucleotide targeted to a nucleic acid sequence encoding intercellular adhesion molecule-1, endothelial leukocyte adhesion molecule-1 or vascular cell adhesion molecule-1 in combination with an immunosuppressive agent, said oligonucleotide consisting of SEQ ID NO:

  • 1, 7, 8, 13, 14, 15, 22, 23, 24, 25, 26, 84, 31, 32, 33, 35, 36, 52, 53, 54, 56, 57, 58, 50, 51, 60, 63, 65, 67, 68, 70, 71 or 72.

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