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Sustained release drug delivery system suitable for oral administration

  • US 5,885,616 A
  • Filed: 08/18/1997
  • Issued: 03/23/1999
  • Est. Priority Date: 08/18/1997
  • Status: Expired due to Term
First Claim
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1. A single bead drug delivery system suitable for oral administration comprising:

  • a) a first drug compartment containing an effective amount of an active agent, or a pharmaceutically acceptable salt thereof, optionally in association with a pharmaceutically acceptable binder or excipient;

    b) a first polymer compartment which substantially envelops said first drug compartment to form a first drug/polymer interface;

    c) a second drug compartment containing an effective amount of an active agent, or a pharmaceutically acceptable salt thereof, optionally in association with a pharmaceutically acceptable binder or excipient, wherein said second drug compartment substantially envelops said first polymer compartment to form a second drug/polymer interface;

    d) a second polymer compartment which substantially envelops said second drug compartment to form a third drug/polymer interface; and

    wherein said single bead drug delivery system can release said active agent in multiple phases.

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