System for two dimensional and three dimensional imaging of tubular structures in the human body

• US 5,891,030 A
• Filed: 01/24/1997
• Issued: 04/06/1999
• Est. Priority Date: 01/24/1997
• Status: Expired due to Term

• Current Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Original Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Inventors: Hara, Amy Kiyo, Johnson, Charles Daniel, Reed, Judd Evon
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): SHAW, SHAWNA JEANNINE
• Application Number:
  US08/787,286
• Time in Patent Office: 802 Days
• Field of Search: 600/407, 600/416, 378/66, 382/128, 382/131, 382/154, 382/285, 382/293, 382/294, 382/307, 382/302, 128/920, 128/922
• US Class Current: 600/407
• CPC Class Codes: A61B 6/027 characterised by the use of a particular data acquisition trajectory, e.g. helical or spiral
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/463 characterised by displaying multiple images or images and diagnostic data on one display
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 6/563 involving image data transmission via a network
• CPC Class Codes: Y10S 128/92 Computer assisted medical diagnostics

Abstract

A system, method, and article of manufacture for imaging tubular structures of the human body, such as the digestive tract of a living person, with a medical imaging device such as a computed tomography (CT) scanner and a computer workstation. The CT scanner is used to generate cross-sectional axial images of a human colon which are then transferred to the computer workstation. A colon midline is defined which follows the colon lumen. The computer workstation supports colon midline definition by generating and displaying reformatted cross-sectional images, volume rendered scouts, and interluminal views. Semi-automatic midline defining tools are also included. After the midline is defined, a montage of images is displayed for diagnostic purposes. The images include axial sections, transluminal cross section, and intraluminal volume rendered images.

Claims

1. A method for imaging a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the method comprising the steps of:

(a) providing to the digital computer an image data set which is representative of the structure and generated by a medical imaging device;

(b) generating with the processor and the image data set two dimensional reformatted images of the structure through a view point;

(c) generating with the processor a three dimensional image of the internal anatomy of the structure at the view point; and

(d) simultaneously displaying with the visual display device the corresponding two dimensional reformatted images and the three dimensional image of the structure at the view point.

2. The method of claim 1, further comprising a step of using the image data set to define a structure midline following the structure lumen.

3. The method of claim 2, wherein the two dimensional reformatted images of the structure are centered on the structure midline.

6. The method of claim 3, wherein the medical imaging device comprises a helical scanning device and wherein an axis of rotation of the imaging device is substantially perpendicular to a longitudinal axis of the human body.

7. The method of claim 3, wherein the step of generating the image data set comprises a reconstruction interval of less than 10 millimeters.

8. The method of claim 3, wherein the step of displaying the three dimensional image of the structure comprises displaying the three dimensional image simultaneously in an axial view, a sagittal view, and a coronal view.

9. The method of claim 8, wherein the step of displaying the three dimensional image of the structure comprises displaying a distance value representing the distance from a first point located at an arbitrary location along the structure to a second point located at a terminating location of the structure.

10. The method of claim 3, wherein the step of displaying the two dimensional images comprises displaying the two dimensional images simultaneously in an axial view, a sagittal view, a coronal view, and a continuous orthogonal view along a straightened version of the structure.

11. The method of claim 3, wherein the step of defining the structure midline comprises manually defining a series of points along the structure lumen.

12. The method of claim 11, wherein the step of defining the structure midline following the structure lumen comprises generating a virtual spline passing through the series of points along the structure lumen, wherein the virtual spline is substantially parallel to the structure midline.

13. The method of claim 12, further comprising a step of displaying an intraluminal three dimensional view of the structure by generating a view point and a view direction with the structure midline such that a field of view defined by the view point and view direction substantially encompasses a view of the structure along the structure midline looking away from a terminating location of the structure.

14. The method of claim 12, further comprising the step of displaying an intraluminal three dimensional view of the structure by generating a view point and a view direction with the virtual spline such that a field of view defined by the view point and view direction substantially encompasses a view of the structure along the structure midline looking toward a terminating location of the structure.

15. The method of claim 12, further comprising the step of displaying an intraluminal three dimensional view of the structure by using a manually selected view point and a view direction which departs from the structure midline.

16. The method of claim 15, wherein the step of displaying an intraluminal three dimensional view of the structure by using a manually selected view point and a view direction comprises displaying a view of the structure forward and backward along a path defined by the manually selected view point and view direction.

17. The method of claim 16, wherein the step of displaying with the visual display device the two dimensional reformatted images and the three dimensional image of the structure comprises simultaneously dynamically updating the two dimensional reformatted images and three dimensional image forward and backward along the path defined by the manually selected view point and view direction.

18. The method of claim 3, wherein the step of displaying the three dimensional image of the structure comprises the steps of:

(a) obtaining a view point;

(b) defining a view direction as a vector pointing toward a centroid of one of the two dimensional reformatted images;

(c) casting a ray through the image data set from the view point along the view direction;

(d) determining a change in density point along the ray;

(e) projecting the ray past the change of density point; and

(f) using the ray to display the three dimensional image of the structure.

19. The method of claim 3, wherein the step of displaying the three dimensional image of the structure comprises the steps of:

(a) defining the structure in a first half and a second half along a plane of longitudinal cross section of the structure; and

(b) displaying the three dimensional image for a view of either the first or second half having a view direction through the plane of a longitudinal cross section of the structure.

4. A method for imaging a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the method comprising the steps of:

(a) providing to the digital computer an image data set representative of the structure and generated by a medical imaging device;

(b) generating with the processor and the image data set two dimensional reformatted images of the structure through a view point;

(c) generating with the processor a two dimensional axial image of the body, including the structure, at the view point; and

(d) simultaneously displaying with the visual display device the corresponding two dimensional reformatted images and the two dimensional axial image of the structure at the view point.

5. A method for imaging a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the method comprising the steps of:

(a) providing to the digital computer an image data set which is representative of the structure and generated by a medical imaging device;

(b) generating with the processor and the image data set two dimensional reformatted images of the structure through a view point;

(c) generating with the processor a two dimensional axial image of the body, including the structure, and a three dimensional image of the internal anatomy of the structure at the view point; and

(d) simultaneously displaying with the visual display device the corresponding two dimensional reformatted images, and the two dimensional axial image and the three dimensional image of the structure at the view point.

20. A system for imaging a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the system comprising:

(a) data transfer means for providing to the digital computer an image data set which is representative of the structure and generated by a medical imaging device;

(b) reformat means logically coupled to the digital computer for generating with the processor two dimensional reformatted images of the structure through a view point;

(c) render means logically coupled to the digital computer for generating with the processor a three dimensional image of the internal anatomy of the structure at the view point; and

(d) display means logically coupled to the reformat means and render means for simultaneously displaying with the visual display device the corresponding two dimensional reformatted images and the three dimensional image of the structure at the view point.

21. The system of claim 20, further comprising definition means logically coupled to the digital computer for defining a structure midline following the structure lumen.

22. The system claim of 20, wherein the two dimensional reformatted images of the structure are centered on the structure midline.

25. The system of claim 22, wherein the medical imaging device comprises a helical scanning device and wherein an axis of rotation of the imaging device is substantially perpendicular to the longitudinal axis of the human body.

26. The system of claim 22, wherein the display means comprises a reconstruction interval in the range of between 1 and 10 millimeters.

27. The system of claim 22, wherein the display means comprises means for displaying the three dimensional image simultaneously in an axial view, a sagittal view, and a coronal view.

28. The system of claim 27, wherein the display means comprises means for displaying a distance value representing the distance from a first point located at an arbitrary location along the structure to a second point located at a terminating location of the structure.

29. The system of claim 22, wherein the display means comprises means for displaying the two dimensional reformatted images simultaneously in an axial view, a sagittal view, a coronal view, and a continuous orthogonal view along a straightened version of the structure.

30. The system of claim 22, wherein the definition means comprises manually defining a series of points along the structure lumen.

31. The system of claim 30, wherein the definition means comprises means for generating a virtual spline passing through the series of points along the structure lumen, wherein the virtual spline is substantially parallel to the structure midline.

32. The system of claim 31, wherein the display means comprises means for generating a view point and a view direction with the structure midline such that the field of view defined by the view point and view direction substantially encompasses a view of the structure along the structure midline looking away from a terminating location of the structure.

33. The system of claim 31, wherein the display means comprises means for generating a view point and a view direction with the virtual spline such that the field of view defined by the view point and view direction substantially encompasses a view of the structure along the structure midline looking toward a terminating location of the structure.

34. The system of claim 31, wherein the display means comprises means for displaying a three dimensional view of the structure by using a manually selected view point and a view direction which departs from the structure midline.

35. The system of claim 34, wherein the display means comprises means for displaying a view of the structure forward and backward along a path defined by the manually selected view point and view direction.

36. The system of claim 22, wherein the display means comprises means for simultaneously dynamically updating the two dimensional reformatted images and three dimensional image forward and backward along the path defined by the manually selected view point and view direction.

37. The system of claim 22, wherein the display means comprises means for simultaneously dynamically updating the two dimensional reformatted images and three dimensional image forward and backward along a path substantially parallel to the structure midline.

38. The system of claim 22, wherein the display means comprises:

(a) means for obtaining a view point;

(b) means for defining a view direction as a vector pointing toward a centroid of one of the two dimensional reformatted images;

(c) means for casting a ray through the image data set from the view point along the view direction;

(d) means for determining a change in density point along the ray;

(e) means for projecting the ray past the change of density point; and

(f) means for using the ray to display the three dimensional image of the structure.

39. The system of claim 22 wherein the display means comprises:

(a) means for defining the structure in a first half and a second half along a plane of longitudinal cross section of the structure; and

(b) means for displaying the three dimensional image for a view of either the first or second half having a view direction through the plane of the longitudinal cross section of the structure.

23. A system for imaging a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the system comprising:

(a) data transfer means for providing to the digital computer an image data set which is representative of the structure and generated by a medical imaging device;

(b) reformat means logically coupled to the digital computer for generating with the processor two dimensional reformatted images of the structure through a view point;

(c) render means logically coupled to the digital computer for generating with the processor a two dimensional axial image of the body, including the structure, at the view point; and

(d) display means logically coupled to the reformat means and render means for simultaneously displaying with the visual display device the corresponding two dimensional reformatted images and the two dimensional axial image of the structure at the view point.

24. A system for imaging a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the system comprising:

(a) data transfer means for providing to the digital computer an image data set which is representative of the structure and generated by a medical imaging device;

(b) reformat means logically coupled to the digital computer for generating with the processor two dimensional reformatted images of the structure through a view point;

(c) render means logically coupled to the digital computer for generating with the processor a two dimensional axial image of the body, including the structure, and a three dimensional image of the internal anatomy of the structure at the view point; and

(d) display means logically coupled to the reformat means and render means for simultaneously displaying with the visual display device the corresponding two dimensional reformatted images, and the two dimensional axial and the three dimensional images of the structure at the view point.

40. One or more program storage devices readable by a computer having a memory and coupled to a data storage device, each of the program storage devices including one or more programs of instructions executable by a computer to perform imaging of a tubular structure of a human body with a digital computer having a processor, a data input device, and a visual display device, the instructions including:

(a) first instruction means for enabling the digital computer to receive an image data set representative of the structure and generated by a medical imaging device;

(b) second instruction means for using the image data set to define a structure midline following the structure lumen;

(c) third instruction means for generating with the processor and the image data set two dimensional reformatted images of the structure through a view point centered on the structure midline;

(d) fourth instruction means for generating with the processor a three dimensional image of the internal anatomy of the structure at the view point; and

(e) fifth instruction means for simultaneously displaying with the visual display device the corresponding two dimensional reformatted images and the three dimensional image of the structure at the view point.

41. A method for operating a digital computer system of the type having a processor, a visual display device and an operator-actuated input device to provide diagnostic images of a tubular structure of a human body at view points selected by a clinician through use of the operator-actuated input device, the method comprising the steps of:

receiving image data which is representative of the tubular body structure to be imaged;

generating from the image data, through each of a plurality of view points, a set of two dimensional reformatted images of the structure;

generating from the image data, at each of the view points, one or more additional images of the structure, the additional images being selected from a set of images including a two dimensional axial image of the body, including the structure, and a three dimensional image of the internal anatomy of the structure;

receiving information representative of the viewpoints selected by the operator through use of the operator-actuated input device; and

simultaneously displaying on the visual display device the corresponding set of two dimensional reformatted images and each additional image of the structure at the selected viewpoints.

42. The method of claim 41 wherein:

the step of receiving information representative of viewpoints selected by the operator includes receiving information representative of a sequence of adjacent viewpoints along a navigated path of the structure; and

the step of displaying the images includes updating the displayed images to simultaneously display the corresponding two dimensional reformatted images and each additional image of the structure at the adjacent viewpoints along the navigated path.

43. The method of claim 42 wherein the step of receiving information representative of viewpoints along a navigated path includes receiving information representative of viewpoints along a navigated path selected by a clinician through use of a mouse.

44. The method of claim 42 wherein the step of receiving information representative of viewpoints along a navigated path includes receiving information representative of viewpoints along a navigated path selected by a clinician through use of a keyboard.

45. The method of claim 41 wherein:

the step of receiving information representative of viewpoints selected by the operator includes receiving information representative of viewpoints along a midline of the structure; and

the step of displaying the images includes displaying at least some of the corresponding images of the structure at the selected viewpoints along the structure midline.

46. The method of claim 41 wherein:

the step of receiving information representative of viewpoints selected by the operator includes receiving information representative of viewpoints off a midline of the structure; and

the step of displaying the images includes displaying at least some of the corresponding images of the structure at the selected viewpoints off the midline of the structure.

47. The method of claim 46 and further including displaying a fiducial mark on at least one of the displayed images to identify the position of the viewpoint.

48. The method of claim 47 and further including displaying a mark on at least one of the displayed images to identify the direction of the viewpoint.

49. The method of claim 41 and further including displaying a fiducial mark on at least one of the displayed images to identify the position of the viewpoint.

50. The method of claim 41 and further including displaying a mark on at least one of the displayed images to identify the direction of the viewpoint.

51. The method of claim 41 wherein displaying the set of two dimensional reformatted images includes displaying two dimensional reformatted axial, sagittal and coronal views.

52. A method for operating a digital computer system of the type having a processor, a visual display device and an operator-actuated input device to provide diagnostic images of a tubular structure of a human body at view points selected through use of the operator-actuated input device, the method comprising the steps of:

receiving image data which is representative of the tubular body structure to be imaged;

generating from the image data, at each of the view points, a two dimensional axial image of the body including the tubular structure;

generating from the image data, through each of the view points, a set of two dimensional reformatted images of the tubular structure;

generating from the image data, at each of the view points, a three dimensional image of the internal anatomy of the tubular structure;

receiving information representative of viewpoints selected through use of the operator-actuated input device, including information representative of a sequence of adjacent viewpoints along a navigated path of the structure;

simultaneously displaying on the visual display device the corresponding two dimensional axial image, the set of two dimensional reformatted images and the three dimensional image at a selected viewpoint; and

updating the visual display device to simultaneously display the corresponding images at the sequence of viewpoints along the navigated path of the structure.

53. The method of claim 52 wherein:

the step of receiving information representative of selected viewpoints includes receiving information representative of viewpoints along a midline of the structure; and

the step of displaying the images includes displaying the set of two dimensional reformated images and the three dimensional endoluminal images of the structure at the selected viewpoints along the midline of the structure.

54. The method of claim 53 wherein:

the step of receiving information representative of selected viewpoints includes receiving information representative of viewpoints off a midline of the structure; and

the step of displaying the images includes displaying the set of two dimensional reformatted images and the three dimensional endoluminal images of the structure at the selected viewpoints off the midline of the structure.

55. The method of claim 54 and further including displaying a fiducial mark on at least one of the displayed images to identify the position of the viewpoint.

56. The method of claim 55 and further including displaying a mark on at least one of the displayed images to identify the direction of the viewpoint.

57. The method of claim 56 wherein the step of receiving information representative of viewpoints along a navigated path includes receiving information representative of viewpoints along a navigated path selected through use of a mouse.

58. The method of claim 56 wherein the step of receiving information representative of viewpoints along a navigated path includes receiving information representative of viewpoints along a navigated path selected through use of a keyboard.