Drug delivery stent

• US 5,891,108 A
• Filed: 09/12/1994
• Issued: 04/06/1999
• Est. Priority Date: 09/12/1994
• Status: Expired due to Term

• Current Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Leone, James E., Rowland, Stephen M., Hennemann, Willard W. III
• Primary Examiner(s): STRIGHT, RONALD K
• Application Number:
  US08/304,163
• Time in Patent Office: 1,667 Days
• Field of Search: 604/8, 604/891.1, 604/890.1, 604/280, 604/281, 604/283, 604/104, 604/264, 604/265, 606/191-195, 606/198, 606/108, 623/1, 623/11, 623/12, 623/66
• US Class Current: 604/264
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir

Abstract

The drug delivery stent assembly includes a hollow tubular wire stent which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site in a vessel where the stent is placed and the stent being constructed in a manner which permits the stent to be placed in one of two states, one state being where the stent assumes the shape of an enlarged generally cylindrical envelope and the other state being where the stent assumes the shape of a contracted smaller cylindrical envelope.

Claims

1. A drug delivery stent assembly including a hollow tubular metal wire stent which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed and said stent being constructed in a manner which permits said stent to be placed in one of two states, one state being where said stent assumes the shape of an enlarged generally cylindrical envelope and the other state being where said stent assumes the share of a contracted smaller cylindrical envelope.

2. The drug delivery stent of claim 1 wherein said stent is made of a nickel titanium alloy.

3. The stent of claim 1 wherein said holes are formed with a laser and are small enough to prevent rapid leakage, but large enough to allow slow leakage of a liquid solution from said stent over a period of several hours to a week or more.

4. The stent of claim 1 wherein said hollow tubular wire stent extends in an undulating helical path to form the cylindrical envelope.

5. The stent of claim 1 wherein said hollow tubular wire stent extends back and forth in an undulating manner and in a cylindrical fashion and axially forwardly to the distal end of the stent to form a continuous stent defining a cylindrical envelope (FIG. 3 or FIG. 5) thereby forming generally cylindrical undulating loops (FIG. 3 or FIG. 5).

6. The stent of claim 1 wherein said hollow tubular wire stent extends in a helical or coiled spring path to form a coiled spring type stent defining therein the cylindrical envelope.

7. The stent of claim 1 being made of stainless steel.

8. The stent of claim 1 being made of tantalum.

9. The stent of claim 1 having at least two holes in the sidewalls of the stent facing inwardly of the cylindrical envelope near at least one end of the stent.

10. The stent of claim 1 wherein said hollow tubular wire has an outer diameter of 0.008 inches±

0.002 inches and an inner diameter of 0.005 inches±

0.002.

11. A drug delivery stent assembly including a hollow tubular wire stent which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed and said stent being made of a material which can be caused to assume two states, one state being where said stent assumes the shape of an enlarged cylindrical envelope and the other state being where said stent assumes the shape of a contracted smaller cylindrical envelope.

12. A drug delivery stent assembly including a hollow tubular wire stent which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed and said stent being made of a nickel titanium alloy.

13. A drug delivery stent assembly including a hollow tubular wire stent which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed and said stent being made of stainless steel.

14. A drug delivery stent assembly including a hollow tubular wire stent which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed and said stent being made of tantalum.

15. A drug delivery stent assembly including a hollow tubular metal wire stent which extends in a path defining a generally cylindrical envelope, which has a proximal end and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed, means for coupling and uncoupling said proximal end to a liquid delivery tubing and said stent being constructed in a manner which permits said stent to be placed in one of two states, one state being where said stent assumes the shape of an enlarged generally cylindrical envelope and the other state being where said stent assumes the shape of a contracted smaller cylindrical envelope.

16. The drug delivery stent assembly of claim 15 wherein said coupling means is made of a dissolvable material.

17. A drug delivery stent assembly including a hollow tubular metal wire stent which has a proximal end, which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed, means for coupling and uncoupling said proximal end to a liquid delivery tubing and said stent being made of a material which can be caused to assume two states, one state being where said stent assumes the shape of an enlarged cylindrical envelope and the other state being where said stent assumes the shape of a contracted smaller cylindrical envelope.

18. The drug delivery stent assembly of claim 17 wherein said coupling means is made of a dissolvable material.

19. A drug delivery stent assembly including a hollow tubular wire stent which has a proximal end, which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed, means for coupling and uncoupling said proximal end to a liquid delivery tubing and said stent being made of a nickel titanium alloy.

20. The drug delivery stent assembly of claim 19 wherein said coupling means is made of a dissolvable material.

21. A drug delivery stent assembly including a hollow tubular wire stent which has a proximal end, which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed, means for coupling and uncoupling said proximal end to a liquid delivery tubing and said stent being made of stainless steel.

22. The drug delivery stent assembly of claim 21 wherein said coupling means is made of a dissolvable material.

24. The drug delivery stent assembly of claim 21 wherein said coupling means is made of a dissolvable material.

23. A drug delivery stent assembly including a hollow tubular wire stent which has a proximal end, which extends in a path defining a generally cylindrical envelope and which has side walls facing outwardly of the cylindrical envelope with holes therein for delivery of liquid to a site of placement in a vessel where the stent is placed, means for coupling and uncoupling said proximal end to a liquid delivery tubing and said stent being made of tantalum.