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Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices

  • US 5,891,863 A
  • Filed: 06/16/1997
  • Issued: 04/06/1999
  • Est. Priority Date: 04/21/1994
  • Status: Expired due to Fees
First Claim
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1. A method of preventing loosening of an orthopedic prosthesis in a patient comprising administering to the patient a bone resorption inhibiting amount of a bisphosphonate selected from the group consisting of alendronate, clodronate, tiludronate, YM 175, BM 21.0995, etidronate, risedronate, piridronate, pamidronate, pharmaceutically acceptable salts thereof, and mixtures thereof.

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