Immuno-stimulatory monoclonal antibodies
First Claim
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1. A monoclonal antibody or an antigen binding fragment thereof, wherein the monoclonal antibodyi. is secreted by the hybridoma cell line deposited at the Collection Nationale de Cultures de Microorganismes (CNCM), under Accession No. I-1397, orii. recognizes the same antigenic epitope as the antibody under (i).
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Abstract
A monoclonal antibody having immuno-stimulatory effects, binds specifically to B lymphoblastoid cells and induces proliferation and activation of peripheral blood lymphocytes, and when injected into tumor-bearing animals elicts an anti-tumor effect.
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9 Claims
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1. A monoclonal antibody or an antigen binding fragment thereof, wherein the monoclonal antibody
i. is secreted by the hybridoma cell line deposited at the Collection Nationale de Cultures de Microorganismes (CNCM), under Accession No. I-1397, or ii. recognizes the same antigenic epitope as the antibody under (i).
Specification