One-piece dispensing device for the contamination-free administration of medicaments (cytostatica)

• US 5,899,877 A
• Filed: 10/15/1996
• Issued: 05/04/1999
• Est. Priority Date: 04/28/1994
• Status: Expired due to Fees

• Current Assignee: Primed Halberstadt Medizintechnik GmbH
• Original Assignee: Primed Halberstadt Medizintechnik GmbH
• Inventors: Wienzek, Gerhard, Leibitzki, Harry, Menz, Marina, Vogt, Sebastian, Neubauer, Norbert
• Primary Examiner(s): Yasko, John D.
• Assistant Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US08/732,480
• Time in Patent Office: 931 Days
• Field of Search: 604/80-81, 604/23, 604/49, 604/53, 604/82-85, 604/30-34, 604/131, 604/151, 604/246, 604/247
• US Class Current: 604/23
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1475 Inlet or outlet ports
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents

Abstract

A one-piece dispensing device for the contamination-free administration of medicaments (cytostatica) is particularly suitable for use in ambulant treatment. The invention provides a connector for connecting medicament (cytostatica) containers to instruments by which the medicaments are administered. The connector is designed to prevent, without a complex apparatus, contamination of the surroundings during connection of the container and until its disposal. The dispensing device has at least one coupling member to create a non-releasable connection with a medicaments container. The coupling member has an insertion pin and barbed surfaces to accommodate the medicaments container. The coupling member is non-releasably connected via a tube to a flexible container which is to be filled with gas. The flexible container is non-releasably connected to a further tube outlet and a mechanically actuated stop valve is incorporated in each of the connecting tubes.

Claims

1. A dispensing device for contamination-free administration of a drug provided in a drug container with a seal, the dispensing device comprising:

at least one coupling member for establishing a non-detachable connection with the drug container, said coupling member including an insertion pin for penetrating the seal of the drug container and at least one barb member for engaging the drug container to establish said non-detachable connection;

a flexible container fillable with a gas;

a first conduit having a first stop valve which is openable and closeable, said first conduit connecting said coupling member with said flexible container to permit passage of the drug between said flexible container and the drug container; and

a second conduit having a second stop valve which is openable and closeable, said second conduit communicating with said flexible container for operation as an outlet.

2. The dispensing device as claimed in claim 1 further comprising a third conduit having a third stop valve which is openable and closeable, said third conduit communicating with said flexible container to permit passage of matter into said flexible container wherein at least said first conduit has said coupling member.

3. The dispensing device as claimed in claim 1 or 2, wherein said coupling member includes a cup-shaped hollow body encircling and sealing around said insertion pin, and said cup-shaped hollow body has a contoured inner surface with said barb member disposed thereon at a position relative to a tip of said insertion pin such that the barb member non-detachably engages the drug container after piercing of the seal of the drug container by said insertion pin.

4. The dispensing device as claimed claim 3, wherein said coupling member includes said hollow body, said contoured inner surface, and said insertion pin, and is manufactured integrally as one piece.

5. The dispensing device as claimed in claim 1, wherein said flexible container is a self-supporting gas-filled flexible container.

6. The dispensing device as claimed in claim 1 or 5, further comprising a third conduit having a check valve, said third conduit communicating with said flexible container to permit passage of matter into said flexible container, said check valve having a socket for receiving a nozzle to permit supply of variable amounts of solvents into said flexible container.

7. The dispensing device according to claim 6, wherein said socket is a Luer-lock joint which opens the check valve.

8. A dispensing device for contamination-free administration of a drug provided in a drug container with a seal, the dispensing device comprising:

at least one coupling member for establishing a non-detachable connection with the drug container, said coupling member including an insertion pin for penetrating the seal of the drug container and a coupling mechanism for non-detachably engaging the drug container to establish said non-detachable connection;

a flexible container fellable with a gas;

a first conduit having a first stop valve which is openable and closeable, said first conduit connecting said coupling member with said flexible container to permit passage of the drug between said flexible container and the drug container;

a second conduit having a second stop valve which is openable and closeable, said second conduit communicating with said flexible container for operation as an outlet.

9. The dispensing device as claimed in claim 8 further comprising a third conduit having a third stop valve which is openable and closeable, said third conduit communicating with said flexible container to permit passage of matter into said flexible container.

10. The dispensing device as claimed in claim 8, wherein said coupling member includes a cup-shaped hollow body encircling and sealing around said insertion pin, said cup-shaped hollow body having a contoured inner surface, and said coupling mechanism includes a barb member disposed on said contoured inner surface at a position relative to a tip of said insertion pin such that the barb member non-detachably engages the drug container after piercing of the seal of the drug container by said insertion pin.

11. A dispensing device for contamination-free administration of a drug provided in a drug container with a seal, the dispensing device comprising:

at least one coupling member for establishing a non-detachable connection with the drug container, said coupling member including an insertion pin for penetrating the seal of the drug container and a coupling mechanism for non-detachably engaging the drug container to establish said non-detachable connection;

a flexible container fillable with a gas;

a first conduit having a first stop valve which is openable and closeable, said first conduit connecting said coupling member with said flexible container to permit passage of the drug between said flexible container and the drug container;

a second conduit having a second stop valve which is openable and closeable, said second conduit communicating with said flexible container for operation as an outlet; and

a third conduit having a check valve, said third conduit communicating with said flexible container to permit passage of matter into said flexible container, said check valve having a socket for receiving a nozzle to permit supply of variable amounts of solvents into said flexible container.

12. The dispensing device according to claim 11, wherein said socket is a Luer-lock joint which opens the check valve.