Bead linkers for immobilizing nucleic acids to solid supports
First Claim
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1. A composition comprising a bead conjugated to a solid support and further conjugated to a nucleic acid.
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Abstract
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to "flat" surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.
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14 Claims
- 1. A composition comprising a bead conjugated to a solid support and further conjugated to a nucleic acid.
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9. A process of making a bead conjugated to a solid support and further conjugated to a nucleic acid, comprising the steps of conjugating a bead to a nucleic acid;
- and conjugating a bead to a solid support.
- View Dependent Claims (10, 11, 12, 13, 14)
Specification