Method and apparatus for detecting cardiac capture

• US 5,902,325 A
• Filed: 07/30/1998
• Issued: 05/11/1999
• Est. Priority Date: 11/30/1994
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Condie, Catherine R., Greeninger, Daniel J., Kleckner, Karen J., Combs, William J., Stroebel, John C., Markowitz, H. Toby, Wahlstrand, John D., Baxter, Daniel J.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US09/126,469
• Time in Patent Office: 285 Days
• Field of Search: 607/28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/3714 Atrial capture

Abstract

A method and apparatus for automatic determination of a pacemaker patient'"'"'s pacing stimulation threshold. Circuitry is provided in a pacemaker for obtaining a signal reflecting cardiac impedance, which is known to reliably reflect certain aspects of cardiac function. Circuitry is also provided for monitoring the cardiac impedance waveform during a predetermined capture detect window following delivery of stimulating pulses. One or more values are derived which characterize the morphology of the impedance waveform during the capture detect window associated with each stimulation pulse delivered. These values are compared to predetermined control values in order to assess whether a stimulation pulse has achieved cardiac capture. The assessment of whether cardiac capture has been achieved is also based partly upon the conventional sensing of atrial and/or ventricular cardiac signals occurring during the capture detect window. In one embodiment of the invention, the control values against which impedance waveform characterization values are compared are obtained by delivering a series of stimulation pulses having sufficient energy to ensure that capture is achieved, and by monitoring the impedance waveform during delivery of these pulses.

Claims

1. A pacemaker system comprising:

a body-implantable pulse generator;

at least one conductive lead having a distal end and a proximal end, said proximal end for coupling to said pulse generator and having at least one lead electrode disposed near said distal end for placement within a chamber of a patient'"'"'s heart, said lead having conductor means adapted to deliver stimulating pulses to said heart and to convey cardiac electrical signals from said electrode to said pulse generator;

a common electrode, coupled to said pulse generator;

said pulse generator comprising;

a control circuit having signal generating means for issuing control signals including an excitation control signal for timing excitation pulses, a capture detect window signal for timing a capture detect window, and at least one stimulation control signal for timing and controlling pulse width and amplitude for stimulation pulses;

a stimulation circuit, coupled to said control circuit and to said lead, responsive to said at least one stimulation control signal to generate a stimulation pulse having amplitude and pulse width determined by said at least one stimulation control signal;

an excitation circuit, coupled to said control circuit, said common electrode, and said lead, said control circuit being responsive to said excitation control signal to generate excitation pulses to be applied to said heart via said lead;

an impedance circuit, coupled to said control circuit and to said lead and responsive to assertion of said capture detect window signal following generation of a stimulation pulse by said stimulation circuit to derive a cardiac impedance signal reflecting a voltage differential between said lead electrode and said common electrode;

an impedance processing circuit, coupled to said impedance circuit and to said control circuit and responsive to said capture detect window signal to derive at least one morphology value reflecting morphology of said impedance signal so as to characterize said impedance signal with said morphology value;

wherein said control circuit comprises a control value reading circuit for reading at least one control value and comparator means to compare said at least one morphology value to said at least one control value to determine whether said stimulation pulse achieved cardiac capture.

2. A pacemaker system as set forth in claim 1 wherein said at least one morphology value derived by said impedance processing circuit is a measure of said impedance signal direction.

3. A pacemaker system as set forth in claim 2 wherein said comparator means further comprises a mechanism for comparing a second morphology value to a second control value and wherein said impedance processing circuit derives said second morphology value and said second morphology value is peak to peak amplitude.

4. A pacemaker system in accordance with claim 1, wherein said common electrode comprises a conductive canister containing said pulse generator.

5. A pacemaker system in accordance with claim 1, wherein said at least one morphology value derived by said impedance processing circuit comprises a digital value corresponding to the peak-to-peak amplitude of an excursion of said impedance signal.

6. A pacemaker system in accordance with claim 1, further comprising:

said body implantable pulse generator further comprising;

telemetry trancieving circuitry for recieving telemetry signals and communicating a signal representative of said telemetry signals to said control circuit and for transmitting signals representative of signals indicative of operational characteristics of said body implantable pulse generator and of physiologic conditions of a body into which said body implantable pulse generator may be implanted,

said control circuit further comprising control logic means for receiving and selectively altering operations based on command and parameter signals it may receive through said telemetry receiving means from an external source such as an external programming unit, and

an external programming unit, comprising a memory circuit linked to a first telemetry transmitter and receiver circuit, for transmitting said command signals and said parameter value signals to said body-implantable pulse generator and for receiving said signals indicative of operational characteristics and said physiologic conditions signals from said body-implantable pulse generator.

7. A pacemaker system in accordance with claim 6, wherein said external programming unit further comprises an external programming unit control circuit means for causing said transmission circuit to transmit a sequence of command and parameter value signals to said body-implantable pulse generator, such that said pulse generator delivers a sequence of stimulation pulses in a test sequence having successively lower energy levels to said heart until said control circuit determines that one of said test stimulation pulses does not achieve capture.