Hand-held materials tester

• US 5,904,658 A
• Filed: 08/22/1997
• Issued: 05/18/1999
• Est. Priority Date: 08/23/1996
• Status: Expired due to Term

• Current Assignee: OsteoBiologics Inc. (Smith & Nephew PLC)
• Original Assignee: OsteoBiologics Inc. (Smith & Nephew PLC)
• Inventors: Wilkes, Robert P., Niederauer, George M., Tynmann, Robert A., Cristante, Sabine, Cline, Steven F., Niederauer, Mark Q.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US08/916,277
• Time in Patent Office: 634 Days
• Field of Search: 600/553, 600/587, 600/595, 73/81
• US Class Current: 600/587
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 2560/0285 Apparatus for single use
• CPC Class Codes: A61B 2562/0261 Strain gauges
• CPC Class Codes: A61B 5/0053 by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
• CPC Class Codes: A61B 5/103 Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes A61B5/08 takes precedence; measuring aids for tailors A41H1/00; measuring instruments specially adapted for dentistry A61C19/04
• CPC Class Codes: A61B 5/442 Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment
• CPC Class Codes: A61B 5/4514 Cartilage
• CPC Class Codes: A61B 5/4528 Joints A61B5/4533, A61B5/4538 take precedence
• CPC Class Codes: G01N 3/42 by performing impressions under a steady load by indentors, e.g. sphere, pyramid G01N3/54 takes precedence
• CPC Class Codes: G01N 33/4833 of solid biological material, e.g. tissue samples, cell cultures tissue in vivo A61B5/00; cell suspensions G01N33/48735

Abstract

A handheld materials testing device is provided for measuring compressive properties of a material, preferably articular cartilage in vivo. The device is computer-controlled and provides a readout indicative of the desired compressive property, which in the case of bodily tissue, may be indicative of the state of health of the tissue. The device does not require precise perpendicular alignment and is preferably capable of compensating for force applied by the user against the tissue.

Claims

1. A device for measuring a compressive property of a material comprising:

a) an indenting tip;

b) a loading system capable of moving a certain linear distance and pushing said indenting tip into said material;

c) a force detection system for measuring force exerted on said indenting tip by said material;

d) a variable angle compensation system for compensating for the effects of tilt of the indenting tip on the force detected by said force detection system; and

e) a rendering system for converting output of said force detection system to a display representative of said compressive property.

2. A device of claim 1 wherein said variable angle compensation system comprises a convex indenting surface on said indenting tip.

3. A device of claim 2 wherein said indenting surface is a hemisphere.

4. A device of claim 2 wherein said indenting surface is a paraboloid.

5. A device of claim 1, further comprising a temperature compensation system.

6. A device of claim 5 wherein said temperature compensation system comprises one or more strain gauges with associated circuitry for temperature compensation whereby said device is able to measure stiffness at a range of temperatures without significant error.

7. A device of claim 1 further comprising an applied force compensation system.

8. A device of claim 7 wherein said applied force compensation system comprises a chamfered indentation hole and a drive shaft mechanically prevented from flexing.

9. A device of claim 7 wherein said applied force compensation system comprises one or more dedicated strain gauges and associated circuitry.

10. A device of claim 1 wherein said device comprises a handpiece and a probe.

11. A device of claim 10 wherein said probe comprises a structure limiting it to single use.

12. A device of claim 1 wherein said device comprises rechargeable batteries.

13. A device of claim 1 wherein said device comprises disposable batteries.

14. A device of claim 1 which is watertight.

15. A device of claim 1 wherein:

a) said loading system comprises;

1) a motor;

2) a drive shaft moved by said motor; and

3) a system for determining the movement of said drive shaft;

b) said force detection system comprises;

1) a sensing arm solidly connected to said indenting tip; and

2) one or more strain gauges for measuring the flexion of said sensing arm;

c) said variable angle compensation system comprises a convex indenting surface on the end of said indenting tip; and

d) said rendering system comprises a visual display.

16. A method for determining the health or disease of cartilage using a device of claim 1 comprising:

a) determining a compressive property of said cartilage;

b) interpolating from said compressive property a measure of health or disease by comparing said compressive property to known measurements of said compressive property of cartilage in established states of health or disease.

17. A watertight device for measuring stiffness of a material comprising:

a) a handpiece and a probe connected to said handpiece through the use of a bayonet type coupler;

b) batteries disposed within said handpiece;

c) an indenting tip made of a rigid material and having a convex tip contoured as a hemisphere or a paraboloid;

d) a loading system operatively connected to said tip comprising;

1) a microprocessor-controlled linear actuator capable of step-wise movement;

2) a drive shaft assembly moved by said linear actuator; and

3) means operatively connected to said linear actuator for determining the number of steps taken by said linear actuator;

e) a force detection system comprising;

1) a sensing arm solidly connected to said indenting tip; and

2) one or more strain gauges to measure the bend of said sensing arm;

f) a rendering system operatively connected to said force detection system comprising a liquid crystal display (LCD) capable of providing measurement data, error feedback, low battery, and battery exhausted displays.

18. A method for determining a compressive property of a material comprising:

a) positioning a device comprising an indenting tip such that said indenting tip contacts said material and means for compensating for effects of angle of contact between said indenting tip and said material;

b) extending said indenting tip into said material;

c) measuring force exerted by said material on said indenting tip;

d) computing the stiffness of said material as a function of said force measurement.

19. A method of claim 18 wherein said material comprises articular cartilage in situ.