Sensor device

• US 5,906,719 A
• Filed: 10/16/1996
• Issued: 05/25/1999
• Est. Priority Date: 01/25/1994
• Status: Expired due to Fees

• Current Assignee: The Victoria University of Manchester
• Original Assignee: The Victoria University of Manchester
• Inventors: Treloar, Paul Howard, Christie, Ian Mcintyre, Vadgama, Pankaj Maganlal
• Primary Examiner(s): TUNG, TA HSUNG
• Application Number:
  US08/682,540
• Time in Patent Office: 951 Days
• Field of Search: 204/403, 204/415, 204/416, 204/418, 204/419, 205/778, 205/778.5, 205/779, 205/781.5, 205/782.5, 205/783, 205/789, 205/787
• US Class Current: 204/415
• CPC Class Codes: C12Q 1/002 Electrode membranes
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001

Abstract

An amperometric sensor device comprising a working electrode, a reference/pseudo-reference electrode and a permselective membrane incorporating a charged organic species. The electrodes are in intimate contact with the membrane and are on a side of the membrane opposite to the side exposed to a fluid sample. The charged organic species provides a conducting path through the membrane between the electrodes.

Claims

1. An amperometric sensor device for detecting a predetermined component present in a fluid sample and providing an output representative thereof, the device comprising a permselective membrane incorporating a charged organic species, said permselective membrane being selective, by partitioning, for lipophilic species, and an electrode arrangement having a working electrode and a reference/pseudo-reference electrode, said electrodes of the electrode arrangement being in intimate contact with the membrane but not being exposed at the side thereof to be presented to the fluid sample and wherein said charged organic species provides a conducting path through the membrane between said electrodes of the electrode arrangement.

2. The device as claimed in claim 1 wherein the membrane is of a synthetic polymer.

3. The device as claimed in claim 2 wherein the polymer is PVC.

4. The device as claimed in claim 2 wherein the membrane is plasticized.

5. The device as claimed in claim 4 wherein the plasticizer for the membrane is provided by the charged organic species.

6. The device as claimed in claim 1 wherein the charged organic species is provided by tricaprylylmethyl ammonium chloride.

7. The device as claimed in claim 1 wherein the charged organic species is provided by sodium tetraphenylborate.

8. The device as claimed in claim 1 wherein the membrane additionally incorporates at least one of a mediator, an enzyme, a cofactor, an antibody, a reagent, conducting particles, and a mixture of polymers.

9. The device as claimed in claim 1 wherein the electrode arrangement is in intimate contact with a face of the membrane.

10. The device as claimed in claim 1 wherein the electrodes are incorporated in the membrane.