Peroxide test strip
First Claim
1. A composition capable of exhibiting a detectable and measurable color transition in response to a peroxide concentration of 0% to greater than 4%, by weight, said composition comprising:
- (a) an iodide salt;
(b) a buffer;
(c) a water-soluble polymer comprising a cellulose-based polymer; and
(d) a carrier comprising water,wherein the composition has a pH of about 2 to about 9.
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Accused Products
Abstract
A composition, method, and test device for quantitatively determining the peroxide concentration of a test sample are disclosed. The test device includes a test pad having a suitable carrier matrix incorporating an indicator reagent composition capable of interacting with peroxide to produce a detectable and measurable response for peroxide over a range of 0% to over 4%, by weight of the test sample. An indicator reagent composition contains: (a) an iodide salt, (b) a buffer, and (c) a water-soluble polymer, preferably a cellulose-based polymer. An indicator reagent composition is incorporated into a carrier matrix, like filter paper, to provide a test pad useful in a dry phase peroxide assay of a test sample, especially for test samples containing a high concentration of peroxide.
18 Citations
36 Claims
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1. A composition capable of exhibiting a detectable and measurable color transition in response to a peroxide concentration of 0% to greater than 4%, by weight, said composition comprising:
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(a) an iodide salt; (b) a buffer; (c) a water-soluble polymer comprising a cellulose-based polymer; and (d) a carrier comprising water, wherein the composition has a pH of about 2 to about 9. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A method of determining peroxide content of an aqueous test sample containing 0% to greater than 4% by weight peroxide, said method comprising:
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(a) contacting the aqueous test sample with an indicator reagent composition comprising; (i) an iodide salt, (ii) a buffer, (iii) a water-soluble polymer comprising a cellulose-based polymer, and (iv) a carrier comprising water, (b) determining the peroxide content of the aqueous test sample from the intensity and degree of a color transition of the indicator reagent composition. - View Dependent Claims (20, 21, 22)
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23. A method of quantitatively determining the peroxide content of an aqueous sample containing 0% to greater than 4% by weight peroxide, said method comprising:
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(a) contacting the aqueous sample with an analyte detection device comprising a test pad, said test pad having incorporated therein an indicator reagent composition comprising; (i) an iodide salt, (ii) a buffer, (iii) a water-soluble polymer comprising a cellulose-based polymer, and (iv) a carrier comprising water, (b) determining the peroxide content of the aqueous sample from the intensity and degree of a color transition of the indicator reagent composition. - View Dependent Claims (24, 25)
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26. A method of determining the peroxide content of an aqueous sample comprising:
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(a) contacting the aqueous sample with an analyte detection device comprising a test pad having incorporated therein; (i) an iodide salt, (ii) a buffer, (iii) a water-soluble polymer comprising a cellulose-based polymer, and (iv) a carrier comprising water, (b) examining the analyte detection device for a color transition; and (c) correlating the color transition to the peroxide content of the aqueous sample. - View Dependent Claims (27, 28)
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29. An analyte-detection device to determine the peroxide content of an aqueous test sample comprising:
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a support strip; a test pad; and an indicator reagent composition incorporated into the test pad, said reagent composition comprising; (a) an iodide salt, (b) a buffer, (c) a water-soluble polymer comprising a cellulose-based polymer, and (d) a carrier comprising water.
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30. A composition capable of exhibiting a detectable and measurable color transition in response to a peroxide concentration of 0% to greater than 4%, by weight, said composition comprising:
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(a) an iodide salt; (b) a buffer; (c) a water-soluble polymer comprising polyvinylpyrrolidone, hydrolyzed polyvinylpyrrolidone, poly(vinyl alcohol), poly(vinyl acetate), a vinyl acetate-vinyl alcohol copolymer, polyvinyloxazolidone, polyvinylmethyloxazolidone, a copolymer of vinylpyrrolidone and a vinyl amide of γ
-amine butyric acid, a polyacrylic acid polymer, a polyacrylic acid copolymer, a partially or fully neutralized salt of a polyacrylic acid polymer or a polyacrylic acid copolymer, poly(methacrylic acid), poly(methacrylamide), poly(N,N-dimethylacryamide), poly(N-isopropylacrylamide), poly(N-acetamidoacrylamide), poly(N-acetamidomethacrylamide), an acrylic interpolymer of polyacrylic acid with poly-(methacrylic acid), polyacrylic acid with poly(methacrylamide), polyacrylic acid with methacrylic acid, a polyoxypropylene-polyoxyethylene block polymer having a structure;
##STR2## wherein x and z, independently, are an integer from 4 to 30, and y is an integer from 4 to 100, polyacrylamide, a copolymer of acrylamide, an acrylamide/sodium acrylate copolymer, an acrylate/acrylamide copolymer, an acrylate/ammonium methacrylate copolymer, an acrylate/diacetoneacrylamide copolymer, an acrylic/acrylate copolymer, an adipic acid/dimethylaminohydroxypropyl diethylenetriamine copolymer, an ammonium acrylate copolymer, an ammonium styrene/acrylate copolymer, an ammonium vinyl acetate/acrylate copolymer, an aminomethylpropanol acrylate/diacetoneacrylamide copolymer, an aminomethylpropanediol acrylate/diacetoneacrylamide copolymer, a butyl benzoic acid/phthalic anhydride/trimethylolethane copolymer, a diethylene glycolamine/epichlorohydrin/piperazine copolymer, an ethylene/vinyl alcohol copolymer, an ethyl ester of polyethylenimine, an isopropyl ester of methyl vinyl ether/maleic anhydride copolymer, a melamine/formaldehyde resin, a methoxyethylene glycol/dodecyl glycol copolymer, an octadecene/maleic anhydride copolymer, an octylacrylamide/acrylate/butylaminoethyl methacrylate copolymer, an octylacrylamide/acrylate copolymer, a polyethylene glycol/dodecyl glycol copolymer, a polyethyleneimine, phthalic anhydride/glycerin/glycidyl decanoate copolymer, a metal salt of polyacrylic acid, a metal salt of a methyl vinyl ether/maleic anhydride copolymer, a vinylpyrrolidone/eicosene copolymer, a vinylpyrrolidone/ethyl methacrylate/methacrylic acid copolymer, a vinylpyrrolidone/hexadecene copolymer, a vinylpyrrolidone/vinyl acetate copolymer, a polyvinylpyrrolidone/vinyl acetate/itaconic acid copolymer, a sodium acrylate/vinyl alcohol copolymer, sodium polymethacrylate, sodium polystyrene sulfonate, a sodium styrene/acrylate/polyethylene glycol-10 dimaleate copolymer, a sodium styrene/polyethylene glycol-10 maleate/nonoxynol-10 maleate/acrylate copolymer, a styrene/acrylamide copolymer, a styrene/acrylate/ammonium methacrylate copolymer, a styrene/maleic anhydride copolymer, a styrene/polyvinyloxazolidone copolymer, a urea formaldehyde polymer, a urea/melamine/formaldehyde polymer, a vinyl acetate/crotonic acid copolymer, a vinyl alcohol copolymer, and mixtures thereof; and(d) a carrier comprising water, wherein the composition has a pH of about 2 to about 9. - View Dependent Claims (31, 32, 33, 34, 35, 36)
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Specification